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Changes in Helicobacter pylori Immunoglobulin G Levels and Gastric Mucosal Atrophy after Successful Eradication of Helicobacter pylori

Kim JH, Lee JS, Kwon YH, Jeon SW, Nam SY, Jin S

BACKGROUND/AIMS: Limited information is available about the relationship between Helicobacter pylori (H. pylori) immunoglobulin (Ig) G and serum pepsinogen (pepsinogen [PG], a marker of gastric mucosal atrophy) concentrations after H....
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ABC Classification Is Less Useful for Older Koreans Born before 1960

Kwon H, Lee SY, Kim JH, Lee SP, Kim JH, Sung IK, Park HS, Shim CS

BACKGROUND/AIMS: In the ABC classification system, group A consists of seronegative subjects without gastric corpus atrophy. This study aimed to determine the prevalence and characteristics of pseudo group A subjects. METHODS:...
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Lower Risk of Gastric Atrophy and Intestinal Metaplasia in Patients with MALT Lymphoma despite Helicobacter pylori Infection

Lee SM, Cheung DY, Moon JK, Kim JI, Park SH, Kim JK

BACKGROUND/AIMS: Atrophic gastritis and intestinal metaplasia are sequential consequences of chronic Helicobacter pylori (H. pylori) infection. These conditions are well known to increase the risk of gastric adenocarcinoma development. Gastric...
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Characteristics of Helicobacter pylori-seropositive subjects according to the stool antigen test findings: a prospective study

Moon HW, Lee SY, Hur M, Yun YM

BACKGROUND/AIMS: In countries with a higher risk of gastric atrophic gastritis, noninvasive tests are helpful for a more reliable diagnosis of Helicobacter pylori infection. The aim of this study was...
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Effect of Alcohol Consumption on Seroconversion in Helicobacter pylori-Seronegative Koreans

Kwon HG, Lee SY, Kim JH, Lee SP, Kim JH, Sung IK, Park HS, Shim CS

BACKGROUND/AIMS: Helicobacter pylori (H. pylori) seroconversion may develop in seronegative adults. Although a positive correlation has been reported between alcohol consumption and seroconversion in Korea, an inverse correlation has been...
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Associations among Gastric Juice pH, Atrophic Gastritis, Intestinal Metaplasia and Helicobacter pylori Infection

Sung J, Kim N, Lee J, Hwang YJ, Kim HW, Chung JW, Kim JW, Lee DH

BACKGROUND/AIMS: Gastric juice plays a crucial role in the physiology of the stomach. The aim of this study is to evaluate associations among the pH of gastric juice, atrophic gastritis...
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Randomized, Double-blind, Placebo-controlled Clinical Trial for the Evaluation of the Efficacy and Safety of Artemisia and Green Tea Extract SD1003F in Volunteers with Helicobacter pylori-associated Gastric Discomfort

Kwon SO, Kwak DY, Hong SP, Kim WH, Park JM, Han YM, Kang Y, Kang EA, Jo S, Hahm KB

BACKGROUND/AIMS: A previous study showed that dietary intervention with Artemisia and green tea extracts, i.e., SD1003F, relieved Helicobacter pylori-associated chronic atrophic gastritis in a mouse model. We continue the research...
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Identification of Nodular Gastritis among Patients Diagnosed with Lymphofollicular Gastritis on a Gastric Biopsied Specimen

Kim YJ, Lee SY, Lee SP, Kim JH, Sung IK, Park HS, Shim CS, Han HS

BACKGROUND/AIMS: Nodular gastritis (NG) is a well-known endoscopic finding observed in patients with a Helicobacter pylori infection, which may lead to invasive gastric cancer. Lymphofollicular gastritis consists of lymphoid follicles...
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Link between Serum Pepsinogen Concentrations and Upper Gastrointestinal Endoscopic Findings

Lee SP, Lee SY, Kim JH, Sung IK, Park HS, Shim CS

The serum pepsinogen (PG) assay findings are correlated with the status of Helicobacter pylori infection, but there are controversies on the link with upper gastrointestinal (UGI) endoscopic findings. The aim...
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Serological Changes after Equivocal Helicobacter pylori-serology Test Findings Dependent on Gastric Secreting Ability

Kim JH, Lee SY, Kwon HG, Lee SP, Kim JH, Sung IK, Park HS, Shim CS

BACKGROUND/AIMS: The serum anti-Helicobacter pylori (H. pylori) immunoglobulin G (IgG) and serum pepsinogen (PG) assays are widely used to screen for gastric cancer. An equivocal serology test finding indicates IgG...
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Endoscopic gastritis, serum pepsinogen assay, and Helicobacter pylori infection

Lee SY

Endoscopic findings of the background gastric mucosa are important in the Helicobacter pylori-seroprevalent population. It is strongly correlated not only with the risk of gastric cancer, but also with the...
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Helicobacter pylori Stool Antigen Levels and Serological Biomarkers of Gastric Inflammation are Associated with Cardio-Metabolic Risk Factors in Type 2 Diabetic Patients

Bahadoran , Mirmiran P, Zarif-yeaganeh M, Zojaji H, Azizi F

BACKGROUND: Helicobacter pylori infection and subsequent gastric inflammation have been proposed as risk factors for the development of insulin resistance and cardiovascular disease. In this study we assessed the possible...
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Multicentric Type 3 Gastric Neuroendocrine Tumors

Lee SH, Moon D, Lee HS, Lee CK, Jeon YD, Park JH, Kim H, Lee SK

A 50-year-old woman with incidentally detected multiple gastric polyps and biopsy-proven neuroendocrine tumor (NET) was referred to our hospital. More than 10 polypoid lesions (less than 15 mm) with normal...
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The Role of Pepsin in Laryngopharyngeal Reflux

Lee SH, Jin SM, Johnston N

Laryngopharyngeal reflux (LPR) is a very prevalent condition with a rising incidence. The diagnosis remains challenging and often controversial because the pathophysiology of LPR is often poorly understood and there...
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Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China

Xie XQ, Zheng KC, Wu BS, Chen TH, Lai SR, Lin ZS, Aoki K

OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and...
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Anti-Helicobacter pylori activities of FEMY-R7 composed of fucoidan and evening primrose extract in mice and humans

Kim TS, Choi EK, Kim J, Shin K, Lee SP, Choi Y, Jeon JH, Kim YB

Helicobacter pylori-eliminating effects of FEMY-R7, composed of fucoidan and evening primrose extract, were investigated in mice and humans. Male C57BL/6 mice were infected with the bacteria by intragastric inoculation (1x10(9)...
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Low Pepsinogen I Level Predicts Multiple Gastric Epithelial Neoplasias for Endoscopic Resection

Park SY, Lim SO, Ki HS, Jun CH, Park CH, Kim HS, Choi SK, Rew JS

  • KMID: 1774561
  • Gut Liver.
  • 2014 May;8(3):277-281.
BACKGROUND/AIMS: Synchronous/metachronous gastric epithelial neoplasias (GENs) in the remaining lesion can develop at sites other than the site of endoscopic resection. In the present study, we aimed to investigate the...
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Effect of Helicobacter pylori Eradication on Functional Dyspepsia

Kim SE, Park YS, Kim N, Kim MS, Jo HJ, Shin CM, Lee SH, Hwang JH, Kim JW, Jeong SH, Lee DH, Jung HC

  • KMID: 2325796
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):233-243.
BACKGROUND/AIMS: This study evaluated the effect of Helicobacter pylori eradication on functional dyspepsia (FD), and the relationship between the changes of histological gastritis and FD symptom responses. METHODS: A total of...
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Evaluation of the Performance of Lumipulse G1200 for Tumor Marker Assays

Cho JH, Lee CM, Park CM, Moon HW, Hur M, Yun YM, Lee W, Chun S, Min WK

  • KMID: 2312197
  • Lab Med Online.
  • 2012 Jul;2(3):131-138.
BACKGROUND: Tumor markers are used for diagnosing cancers and monitoring responses to cancer therapy. In this study, we evaluated the performance of Lumipulse G1200 (Fujirebio, Japan), a fully automated serum...
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Changing Trends of Serum Pepsinogen I/II Ratio in Asymptomatic Subjects

Yang JH, Lee SY, Hong SN, Kim JH, Sung IK, Park HS, Shim CS, Jin CJ

BACKGROUND/AIMS: Gastric atrophy can be diagnosed by serum pesinogen I/II ratio. The aim of this study was to investigate whether the changes of serum pepsinogen I/II ratio can be predicted...
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