J Korean Geriatr Soc.  2013 Sep;17(3):152-156. 10.4235/jkgs.2013.17.3.152.

Successful Fecal Transplantation by Enema for Recurrent and Refractory Clostridium difficile Infection

Affiliations
  • 1Department of Internal Medicine, Chungnam National University College of Medicine, Daejon, Korea. medone@cnuh.co.kr

Abstract

Clostridium difficile infection (CDI) is a common cause of antibiotic-associated diarrhea with an increase in severity and frequency in the recent times. CDI can be refractory and relapses, especially in the elderly or patients with significant comorbidities. Conventional treatments with antibiotics often fail to cure the infection. Even when successfully treated, recurrent infection is common. Some studies have reported that fecal transplantation may be effective and safe for the treatment of recurrent and intractable CDI. We present two CDI cases (one recurrent and one refractory) which were treated successfully by fecal transplantation using enema.

Keyword

Clostridium difficile; Feces; Transplantation; Enema

MeSH Terms

Aged
Anti-Bacterial Agents
Clostridium
Clostridium difficile
Comorbidity
Diarrhea
Enema
Feces
Humans
Recurrence
Transplants
Anti-Bacterial Agents
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