Gut Liver.  2015 Mar;9(2):247-250. 10.5009/gnl14152.

A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. viper@catholic.ac.kr

Abstract

Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficile infection. However, there are few published articles on the use of such transplantation for fulminant C. difficile infection. Here, we report on a patient with toxic megacolon complicated by C. difficile infection who was treated successfully with fecal microbiota transplantation.

Keyword

Fulminant Clostridium difficile infection; Megacolon; toxic; Fecal microbiota transplantation

MeSH Terms

Aged
*Clostridium difficile
Enterocolitis, Pseudomembranous/*complications
Fecal Microbiota Transplantation/*methods
Feces/*microbiology
Humans
Male
Megacolon, Toxic/*microbiology/*therapy
Full Text Links
  • GNL
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr