J Korean Neurosurg Soc.  1985 Sep;14(3):519-526.

Clinical Study on the Effect of TRH in Patients with Prolonged Mild Disturbance of Consciousness

Affiliations
  • 1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

Authors report the clinical study on the usefulness of thyrotropin-releasing hormone tartrate(TRH-T) in the treatment of mild disturbance of consciousness. 20 patients suffering head trauma, subarachnoid hemorrhage, and intracerebral hemorrhage were given TRH-T intravenously for ten days. TRH-T was effective for the patients in whom the consciousness disturbance was mild, the duration in fixed consciousness level was short, and the brain was not distorted on CT scan. These features were most prominent in patients with subarachnoid hemorrhage. Three was no significant side effect, and TRH-T turned out to be safe.

Keyword

Thyrotropin-releasing hormone tartrate; Mild disturbance of consciousness; III-3 formula; Usefulness

MeSH Terms

Brain
Cerebral Hemorrhage
Consciousness*
Craniocerebral Trauma
Humans
Subarachnoid Hemorrhage
Thyrotropin-Releasing Hormone
Tomography, X-Ray Computed
Thyrotropin-Releasing Hormone
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