- Low Dose Exposure to Di-2-Ethylhexylphthalate in Juvenile Rats Alters the Expression of Genes Related with Thyroid Hormone Regulation
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Kim M, Jeong JS, Kim H, Hwang S, Park IH, Lee BC, Yoon SI, Jee SH, Nam KT, Lim KM
- KMID: 2421730
- Biomol Ther.
- 2018 Sep;26(5):512-519.
- doi: 10.4062/biomolther.2018.076
Phthalates widely used in the manufacture of plastics have deeply penetrated into our everyday lives. Recently, a concern over the toxicity of phthalates on thyroid, has been raised but in... -
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- Interpretation of puzzling thyroid function tests
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Yoon JH, Kang HC
- KMID: 2409043
- J Korean Med Assoc.
- 2018 Apr;61(4):241-247.
- doi: 10.5124/jkma.2018.61.4.241
With the generalized use of highly sensitive thyroid stimulating hormone (TSH) and free thyroid hormone assays, most thyroid function tests (TFTs) are straightforward to interpret and confirm the clinical impressions... -
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- Lentivirus-mediated microRNA-124 gene-modified bone marrow mesenchymal stem cell transplantation promotes the repair of spinal cord injury in rats
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Song JL, Zheng W, Chen W, Qian Y, Ouyang YM, Fan CY
- KMID: 2382694
- Exp Mol Med.
- 2017 May;49(5):e332.
- doi: 10.1038/emm.2017.48
Our study aims to explore the effects of lentivirus-mediated microRNA-124 (miR-124) gene-modified bone marrow mesenchymal stem cell (BMSC) transplantation on the repair of spinal cord injury (SCI) in rats. BMSCs... -
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- Hypopituitarism Presenting as Adrenal Insufficiency and Hypothyroidism in a Patient with Wilson's Disease: a Case Report
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Lee HW, Kang JD, Yeo CW, Yoon SW, Lee KJ, Choi MK
- KMID: 2373766
- J Korean Med Sci.
- 2016 Aug;31(8):1345-1348.
- doi: 10.3346/jkms.2016.31.8.1345
Wilson's disease typically presents symptoms associated with liver damage or neuropsychiatric disturbances, while endocrinologic abnormalities are rare. We report an unprecedented case of hypopituitarism in a patient with Wilson's disease.... -
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- The Effects of an Extract of Atractylodes Japonica Rhizome, SKI3246 on Gastrointestinal Motility in Guinea Pigs
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Park JJ, Chon NR, Lee YJ, Park H
- KMID: 2433474
- J Neurogastroenterol Motil.
- 2015 Jul;21(3):352-360.
- doi: 10.5056/jnm14112
BACKGROUND/AIMS: There are limited therapeutic options available for irritable bowel syndrome with diarrhea (IBS-D). We tested the effects of Atractylodes japonica rhizome, a perennial plant native to North Asia, on... -
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- A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis
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Park JH, Lee SG, Park EK, Koo DW, Kim BH, Kim IJ, Kim GT
- KMID: 2269093
- Korean J Med.
- 2015 Jun;88(6):737-741.
- doi: 10.3904/kjm.2015.88.6.737
A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the... -
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- Subclinical hypothyroidism diagnosed by thyrotropin-releasing hormone stimulation test in infertile women with basal thyroid-stimulating hormone levels of 2.5 to 5.0 mIU/L
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Lee YJ, Kim CH, Kwack JY, Ahn JW, Kim SH, Chae HD, Kang BM
- KMID: 2314018
- Obstet Gynecol Sci.
- 2014 Nov;57(6):507-512.
- doi: 10.5468/ogs.2014.57.6.507
OBJECTIVE: To investigate the prevalence of subclinical hypothyroidism (SH) diagnosed by thyrotropin-releasing hormone (TRH) stimulating test in infertile women with basal thyroid-stimulating hormone (TSH) levels of 2.5 to 5.0 mIU/L. METHODS:... -
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- Neonatal screening and a new cause of congenital central hypothyroidism
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Tajima T, Nakamura A, Morikawa S, Ishizu K
- KMID: 2134077
- Ann Pediatr Endocrinol Metab.
- 2014 Sep;19(3):117-121.
- doi: 10.6065/apem.2014.19.3.117
Congenital central hypothyroidism (C-CH) is a rare disease in which thyroid hormone deficiency is caused by insufficient thyrotropin (TSH) stimulation of a normally-located thyroid gland. Most patients with C-CH have... -
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- Hypothalamic Hypopituitarism Caused by Pituitary Stalk Dysgenesis
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Lee SJ, Yoon HJ, Cho AR, Um YJ, Park KY, Lim DM, Kim BJ
- KMID: 2267795
- Korean J Med.
- 2013 Oct;85(4):420-424.
Functional defects of the pituitary gland are a rare cause of pubertal delay. The pituitary stalk is an important structure that connects the hypothalamus and pituitary gland. A defect in... -
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- Effects of Ramosetron on Gastrointestinal Transit of Guinea Pig
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Park YM, Lee YJ, Lee YH, Kim TI, Park H
- KMID: 2325969
- J Neurogastroenterol Motil.
- 2013 Jan;19(1):36-41.
BACKGROUND/AIMS: A selective 5-hydroxytryptamine (5-HT) type 3 receptor antagonist, ramosetron, inhibits stress-induced abnormal defecation in animals and is currently used as a therapeutic drug for irritable bowel syndrome with diarrhea.... -
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- The Effect of Octreotide LAR on GH and TSH Co-Secreting Pituitary Adenoma
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Kim NK, Hah YJ, Lee HY, Kim SJ, Kim MK, Park KG, Kim E, Chang H, Kim HS
- KMID: 1497767
- Endocrinol Metab.
- 2010 Dec;25(4):378-381.
- doi: 10.3803/EnM.2010.25.4.378
Growth hormone (GH) and thyroid stimulating hormone (TSH)-secreting pituitary adenomas are very rare and they account for only 0.5% for all pituitary adenomas. These adenomas are usually treated with surgery,... -
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- Remission rate and remission predictors of Graves disease in children and adolescents
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Lee SH, Lee SY, Chung HR, Kim JH, Kim JH, Lee YA, Yang SW, Shin CH
- KMID: 2281258
- Korean J Pediatr.
- 2009 Sep;52(9):1021-1028.
- doi: 10.3345/kjp.2009.52.9.1021
PURPOSE: Medical therapy is the initial treatment for children with Graves disease to avoid complications of other treatments. However, optimal treatment for childhood Graves disease is controversial because most patients... -
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- Identification of a de novo mutation (H435Y) in the THRB gene in a Korean patient with resistance to thyroid hormone
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Shin JY, Ki CS, Kim JK
- KMID: 2278491
- Korean J Pediatr.
- 2007 Jun;50(6):576-579.
- doi: 10.3345/kjp.2007.50.6.576
The syndrome of resistance to thyroid hormone (RTH) is characterized by reduced tissue sensitivity to thyroid hormone (TH). In the majority of subjects, RTH is caused by mutations in the... -
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- Reversible Pituitary Dysfunction in a Patient with Cushing's Syndrome due to Adrenal Adenoma
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Kong JH, Kim KW, Kim HJ, Nam JS, Park JA, Park JS, Kim CS, Moon BS, Hong SW, Ahn CW, Kim KR
- KMID: 1511954
- J Korean Soc Endocrinol.
- 2006 Apr;21(2):146-152.
- doi: 10.3803/jkes.2006.21.2.146
A 45-year-old woman who complained of weight gain and irregular menstruation was diagnosed as having Cushing's syndrome due to a 3 cm sized left adrenal adenoma. She underwent left adrenalectomy,... -
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- Reassessment of Growth Hormone(GH) Status and Metabolic Disturbance in Young Adults with Childhood-onset GH Deficiency
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Kim DH, Yoo EG
- KMID: 2321997
- J Korean Soc Pediatr Endocrinol.
- 2002 Dec;7(2):190-198.
PURPOSE: Adults with GH deficiency(GHD) have abnormal body composition, reduced physical performance, altered lipid metabolism, increased cardiovascular diseases, and reduced quality of life. Administration of GH to these patients reduce... -
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- Effect of TRH on Phospholipase D Activity in GH3 Cell
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Kim DS, Lee CB, Ahn YH, Kim TW, Yoon MS, Han JS
- KMID: 2199978
- J Korean Soc Endocrinol.
- 2002 Aug;17(4):465-472.
BACKGROUND: GH3 cells are a well characterized and widely used model used for the in vitro study of growth hormone (GH) secretion. Thyrotropin releasing hormone (TRH) binds to receptors ... -
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- A case of lymphocytic infundibuloneurohypophysitis presenting as central diabetes insipidus and nodular mass on neurohypophysis
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Cho GY, Hahm JR, Kim JH, Kang TW, Chung IK, Yang TY, Chung JH, Min YK, Lee MS, Lee MK, Se YL, Kim KW
- KMID: 1601335
- Korean J Med.
- 2001 Aug;61(2):168-172.
Lymphocytic infundibuloneurohypophysitis was known as a cause of idiopathic central diabetes insipidus. Until recent time, it is characterized into two groups. One has thickening of the pitutitary stalk, enlargement of... -
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- The role of K+ channels on spontaneous action potential in rat clonal pituitary GH3 cell line
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Rhim H, Baek HJ, Ho WK, Earm YE
- KMID: 1982593
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):81-90.
The types of K+ channel which determine the pattern of spontaneous action potential (SAP) were investigated using whole-cell variation of patch clamp techniques under current- and voltage-clamp recording conditions in rat clonal pituitary... -
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- Thyrotropin-releasing Hormone(TRH) Receptor Gene Expression in GH3 Cells Permanently Transfected with a Mutant Gs alpha Gene
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Park SJ, Yang IM, Yim SV, Chung JH, Jung JC, Ko KC, Kim YS, Choi YK
- KMID: 1540023
- J Korean Soc Endocrinol.
- 2000 Mar;15(1):46-54.
BACKGROUND: Gs alpha gene mutation, that constitutively increases intracellular cAMP, is found in some acromegalic patients. It was demonstrated that increased intracellular cAMP levels suppress the expression of rat TRH... -
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- Antenatal Thyrotropin-Releasing Hormone to Prevent Respiratory Distress Syndrome in Preterm
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Kim AR, Park SJ, Yoon HS, Kim KS, Won HS, Lee IS, Kim A, Pi SY
- KMID: 1748173
- J Korean Pediatr Soc.
- 1999 Jul;42(7):911-920.
PURPOSE: The purpose of this study was to assess the efficacy of antenatal thyrotropin-releasing hormone(TRH) given to mothers at risk for preterm delivery and assess various neonatal outcomes in infants... -
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