J Korean Geriatr Psychiatry.  2007 Jun;11(1):25-28.

Mortality Rates and Risk Factors in Community Based Dementia Patients

Affiliations
  • 1Department of Psychiatry, Evergreen Hospital, Ilsan, Korea.
  • 2Department of Psychiatry, Seoul National University College of Medicine, Boramae Hospital, Seoul, Korea. benji@snu.ac.kr
  • 3Department of Neuropsychiatry, Hallym University College of Medicine, Seoul, Korea.
  • 4Department of Psychiatry, Clinical Research Institute, Seoul National University College of Medicine & Hospital, Seoul, Korea.

Abstract


OBJECTIVES
The aim of this study was to investigate mortality rates and risk factors in dementia patients in a rural cohort.
METHODS
A total of 114 subjects with clinically diagnosed dementia were followed up for eight years from 1997 to 2005. Their mortality was compared with sociodemographic and clinical variables using the Cox proportional hazards models after adjusting age, sex, and education.
RESULTS
During follow-up, the mortality rate of subjects was 80.2% and the mean (SD) duration of survival from at diagnosis to death was 4 years. Mortality in subjects with dementia depended on old age (relative risk [RR] : 1.05 ; 95% confidence interval [CI] : 1.01-1.08), male (RR : 1.61 ; CI : 1.00-2.59), low Clinical Dementia Rating scale (RR : 1.54 ; CI : 1.14-2.10), low Activities of Daily Living (RR : 0.72 ; CI : 0.59-0.89), low Instrumental Activities of Daily Living (RR : 0.83 ; CI : 0.75-0.92), no physical activity (RR : 0.44 ; CI : 0.28-0.70), smoking (RR : 1.74 ; CI : 1.05-2.89).
CONCLUSION
Mortality in dementia depended on age, sex, CDR, ADL, IADL, physical activity, smoking. These findings have important implications that contribute to make the disease management of dementia patients.

Keyword

Dementia; Mortality; Risk factors

MeSH Terms

Activities of Daily Living
Cohort Studies
Dementia*
Diagnosis
Disease Management
Education
Follow-Up Studies
Humans
Male
Mortality*
Motor Activity
Proportional Hazards Models
Risk Factors*
Smoke
Smoking
Smoke
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