J Korean Neurol Assoc.
2003 Dec;21(6):679-682.
A Case of Critical Illness Myopathy
- Affiliations
-
- 1Department of Neurology, Yonsei University College of Medicine, Korea. kimsm@yumc.yonsei.ac.kr
- 2Department of pathology, Yonsei University College of Medicine, Korea.
Abstract
- Critical illness myopathy (CIM) is characterized by generalized flaccid weakness occurring in patients with severe systemic illness. A 27-year-old woman presented with loss of consciousness and dyspnea. The brain MRI suggested Wernicke's encephalopathy. During treatment, she experienced progressive quadriparesis and respiratory muscle weakness, which required the mechanical ventilation. The muscle pathology of vastus lateralis revealed type 2 muscle fiber atrophy on histochemical stain and selective loss of myosin on electron microscopic study, and suggested clinical diagnosis of critical illness myopathy.
