J Korean Med Assoc.  2004 Jul;47(7):653-660. 10.5124/jkma.2004.47.7.653.

Acute Infectious Diarrhea

Affiliations
  • 1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, Korea. hskim@wonju.yonsei.ac.kr

Abstract

Acute infectious diarrhea is the most common cause of diarrhea worldwide and is the leading cause of deaths in childhood. Despite improvements in public health and economic wealth, the incidence of intestinal infection remains high and continuous to be an important clinical problem in developed countries. Acute diarrhea, defined as an increased frequency of defecation (three or more times per day or at least 200 g of stool per day) lasting less than 14 days, may be accompanied by nausea, vomiting, abdominal cramping, clinically significant systemic symptoms, or malnutrition. Acute infectious diarrhea presents clinically as one of two major clinical syndromes, acute watery diarrhea, which usually resolves within 5~10 days, and diarrhea with blood (dysentery). The initial clinical evaluation of the patient with acute diarrhea should focus on the assessment of the severity of the illness, the need for rehydration, and the identification of likely causes on the basis of the history and clinical findings. In this article I focus on the causative agents, diagnosis, and management of acute infectious diarrhea in immunocompetent adults in Korea.

Keyword

Acute infectious diarrhea; Dysentery; Diagnosis; Treatment

MeSH Terms

Adult
Cause of Death
Colic
Defecation
Developed Countries
Diagnosis
Diarrhea*
Dysentery
Fluid Therapy
Humans
Incidence
Korea
Malnutrition
Nausea
Public Health
Vomiting

Reference

1. Farthing MJG. Irvine EJ, editor. Infectious Diarrhea. Evidence-based Gastroenterology. 2001. Hamilton London: BC Decker;403–424.
2. Dupont HL. Guidelines on acute infectious diarrhea in adults. The Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol. 1997. 92:1962–1975.
3. Farthing MJG. Pathophysiology of infective diarrhea. Eur J Gastroenterol Hepatol. 1993. 5:796–807.
4. Rautanen T, El-Radhi S, Vesikari T. Clinical experience with a hypotonic oral rehydration solution in acute diarrhea. Acta Paediatr. 1993. 92:52–54.
5. Schiller LR, Santa Ana CA, Morawski SG, Fordtran JS. Mechanism of the antidiarrheal effect of loperamide. Gastroenterology. 1984. 86:1475–1480.
Article
6. Hamza H, Khalifa HB, Baumer P, Berard H, Lecomte JM. Racecadotril versus placebo in the treatment of acute diarrhea in adults. Aliment Pharmacol Ther. 1999. 13:Suppl 6. 15–19.
Article
7. Mattila L, Peltola H, Siitonen A, Kyronseppa H, Simula I, Kataja M. Short-term treatment of traveler's diarrhea with norfloxacin : a doubleblind, placebo-controlled study during two sessions. Clin Infect Dis. 1993. 17:779–782.
Article
8. Proulx F, Turgeon JPJ, Delage G, Lafleur L, Chicoine L. Randomized, controlled trial of antibiotic therapy for Escherichia coli O157 : H7 enteritis. J Pediatr. 1992. 121:299–303.
Article
9. Thielman NM, Guerrant RL. Acute infectious diarrhea. N Eng J Med. 2004. 350:38–47.
Article
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