J Korean Diabetes Assoc.  2006 May;30(3):190-197. 10.4093/jkda.2006.30.3.190.

The Clinical Characteristics of Young Onset Diabetes According to Etiology Based Classification

• Park M
• Kang YI
• Chon S
• Oh SJ
• Woo JT
• Kim SW
• Kim JW
• Kim YS

• KMID: 2177613
• DOI: http://doi.org/10.4093/jkda.2006.30.3.190

Abstract

BACKGROUND: Recently, the number of young diabetic patients is increasing. It is important to understand the characteristics of young diabetes and classify it correctly to manage these patients successfully. We aimed to classify young onset diabetes according to etiology and evaluate the clinical characteristics.
METHODS
Young patients (15~30 years old) who have been treated diabetes in Kyunghee medical center in 2004 were included. We investigated family history of diabetes, disease duration, body mass index (BMI), the history of diabetic ketoacidosis, HbA1c, fasting C-peptide, autoantibody, lipid profile and treatment method via medical records. RESULT: Total 85 patients (M:F 40:45) were evaluated. Type 1 diabetes was 45.9%, type 2 diabetes was 23.5% and unclassified group was 25.9%. Many type 2 diabetic patients were overweight or obese (94.8%). Most young diabetic patients were using insulin (95.4%). Many type 1 diabetic patients have been treated by insulin only and many type 2 diabetic patients have been received combined therapy of insulin and oral hypoglycemic agent. The recent HbA1c was average 8.32 +/- 2.7%. The prevalence of diabetic retinopathy, neuropathy and nephropathy was 32.9%, 22.4% and 16.4% as each.
CONCLUSION
Nearly half of young onset diabetes was type 1 diabetes but many others were also classified to type 2 diabetes or unclassified group. It is important to provide a consistent algorithm for assessment and investigation for newly diagnosed young diabetic patients. More education and effort are required to control diabetes strictly and prevent its complication.

Keyword

Autoantibody; C-peptide; Type 1 diabetes; Type 2 diabetes

MeSH Terms

Body Mass Index
C-Peptide
Classification*
Diabetic Ketoacidosis
Diabetic Retinopathy
Education
Fasting
Humans
Insulin
Medical Records
Overweight
Prevalence
C-Peptide
Insulin

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