Primary Non - Hodgkin's Lymphomas of the Uterine Corpus: Report of two cases

Han, S Y; Park, N H; Kim, Y B; Kim, J W; Song, Y S; Park, I A; Kang, S B; Lee, H P

Abstract

Primary non-Hodgkins malignant lymphomas of the uterine corpus are very rare lesions, although lymphomas and leukemias frequently involve the female genital tract in advanced cases of disease. Because of this rarity, the etiology, standard treatment, and prognosis have not been defined. Here, we report two cases of primary uterine corpus lymphomas. In one patient, a non-Hodgkins lymphoma, especially, diffuse large B-cell lymphoma stage IE was diagnosed and treatment consisted of debulking surgery and radiation due to poor performance status and old age. In the other patient, a non-Hodgkins lymphoma stage IVE was diagnosed and although she was older than the first case, she was treated with combination chemotherapy. The former shows progressive disease, despite of early stage and adjuvant radiation therapy, the latter shows complete response at 3 months of follow up after chemotherapy.