Korean J Obstet Gynecol.  2009 Oct;52(10):1051-1055.

Two cases of primary malignant lymphoma of the uterine cervix

• Lim SO
• Key EY
• Ro DY
• Park BJ
• Kim YW
• Kim TE
• Jung JK
• Han CW
• Lee AH

Abstract

Primary malignant lymphoma of the uterine cervix is very rare. Lymphomas account for 3.5% of all malignant tumors in the females. Approximately, 25% of all malignant lymphomas arise from extranodal sites, most frequently from gastrointestinal tract and skin. Although the incidence of systemic non-Hodgkin's lymphoma (NHL) and extranodal NHL has increased in recent decades, only 1 to 1.5% arises from female genital tract. Primary pelvic sites include ovary, which is the most common site, uterine corpus, cervix, vagina, and vulva. Primary cervical lymphomas account for 0.12~0.6% of all extranodal lymphomas. However, there is still no consensus on the management of cervical lymphomas due to low incidence of the disease and limited experience in the literature. We experienced two cases of primary malignant lymphoma of the uterine cervix. A 41-year-old woman, Ann Arbor stage IE, was treated with laparoscopically assisted vaginal hysterectomy and both salpingo-oophorectomy and 4 cycles chemotherapy. A second case was a 73-year-old postmenopausal woman, Ann Arbor stage III, received five courses chemotherapy without any surgery. In this article, two cases of uterine cervical lymphoma are presented with a review of the available literature.

Keyword

Primary malignant Lymphoma; Uterine cervix

MeSH Terms

Adult
Aged
Cervix Uteri
Consensus
Female
Gastrointestinal Tract
Humans
Hysterectomy, Vaginal
Incidence
Lymphoma
Lymphoma, Non-Hodgkin
Ovary
Skin
Vagina
Vulva