Intest Res.  2014 Jan;12(1):60-65. 10.5217/ir.2014.12.1.60.

The Effect of Indigocarmine on Improvement of the Polyp Detection Rate during Colonoscopic Examination with Hood Cap

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Busan Saint Mary's Hospital, Busan, Korea. parcero@hanmail.net
  • 2Department of Internal Medicine, Guposungsim Hospital, Busan, Korea.

Abstract

BACKGROUND/AIMS
Hood cap-assisted chromocolonoscopy using indigocarmine is expected to improve the detection rate of colorectal polyps, especially adenomatous polyps. Therefore, aim of the present study was to evaluate the usefulness of hood cap-assisted chromocolonoscopy in routine colonoscopic examinations.
METHODS
From January, 2013 through March, 2013, a total of 86 patients were enrolled (M:F=33:53, mean age=60 years). For each patient, hood cap-assisted colonoscopic examination was performed, followed by hood cap-assisted chromocolonoscopy using 0.2% indigocarmine from the cecum to the hepatic flexure. Total numbers and characteristics of polyps were compared before and after indigo carmine dye spraying.
RESULTS
Prior to dye spraying, 48 polyps were found in 37 patients, and after dye spraying, 53 additional polyps were found in 34 patients. Of these undetected polyps, 45 (85%) were small sized polyps (< or =0.5 cm). Histologically, 19 (36%) were adenomatous polyps, and of these, 15 (28%) were tubular adenomas and 4 (8%) were serrated adenomas. As for the polyp detection rate, there was no difference between the expert and the non-expert groups.
CONCLUSION
Hood cap-assisted chromocolonoscopic examination using indigocarmine was helpful in detecting cecum and ascending colon polyps, especially small sized polyps (<0.5 cm) and neoplastic polyps.

Keyword

Colonoscopy; Hood cap; Indigocarmine; Polyps; Adenoma

MeSH Terms

Adenoma
Adenomatous Polyps
Cecum
Colon, Ascending
Colonoscopy
Humans
Indigo Carmine
Polyps*
Indigo Carmine

Cited by  2 articles

Detection of Polyps Including Adenomas in the Ascending Colon by Cap-assisted Chromocolonoscopy with Indigo Carmine
Hyun Seok Lee
Intest Res. 2014;12(1):3-4.    doi: 10.5217/ir.2014.12.1.3.

Is Retroflexion Helpful in Detecting Adenomas in the Right Colon?: A Single Center Interim Analysis
Hyun Seok Lee, Seong Woo Jeon
Intest Res. 2015;13(4):326-331.    doi: 10.5217/ir.2015.13.4.326.


Reference

1. Kiesslich R, von Bergh M, Hahn M, Hermann G, Jung M. Chromoendoscopy with indigocarmine improves the detection of adenomatous and nonadenomatous lesions in the colon. Endoscopy. 2001; 33:1001–1006. PMID: 11740641.
Article
2. Han SJ, Kim EY, Park JB, et al. Narrow band imaging and white light colonoscopy for detection of polyps. Korean J Gastrointest Endosc. 2011; 42:152–156.
3. Brooker JC, Saunders BP, Shah SG, et al. Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy: a randomized controlled trial. Gastrointest Endosc. 2002; 56:333–338. PMID: 12196768.
Article
4. Lee JH, Kim JW, Cho YK, et al. Detection of colorectal adenomas by routine chromoendoscopy with indigocarmine. Am J Gastroenterol. 2003; 98:1284–1288. PMID: 12818270.
Article
5. Matsumoto T, Nakamura S, Jo Y, Yao T, Iida M. Chromoscopy might improve diagnostic accuracy in cancer surveillance for ulcerative colitis. Am J Gastroenterol. 2003; 98:1827–1833. PMID: 12907339.
Article
6. Togashi K, Hewett DG, Radford-Smith GL, Francis L, Leggett BA, Appleyard MN. The use of indigocarmine spray increases the colonoscopic detection rate of adenomas. J Gastroenterol. 2009; 44:826–833. PMID: 19448968.
Article
7. Ng SC, Tsoi KK, Hirai HW, et al. The efficacy of cap-assisted colonoscopy in polyp detection and cecal intubation: a meta-analysis of randomized controlled trials. Am J Gastroenterol. 2012; 107:1165–1173. PMID: 22664471.
Article
8. Aronchick CA, Lipshutz WH, Wright SH, Dufrayne F, Bergman G. A novel tableted purgative for colonoscopic preparation: efficacy and safety comparisons with Colyte and Fleet Phospho-Soda. Gastrointest Endosc. 2000; 52:346–352. PMID: 10968848.
Article
9. Su MY, Ho YP, Chen PC, et al. Magnifying endoscopy with indigo carmine contrast for differential diagnosis of neoplastic and nonneoplastic colonic polyps. Dig Dis Sci. 2004; 49:1123–1127. PMID: 15387332.
Article
10. Hixson LJ, Fennerty MB, Sampliner RE, McGee D, Garewal H. Prospective study of the frequency and size distribution of polyps missed by colonoscopy. J Natl Cancer Inst. 1990; 82:1769–1772. PMID: 2231773.
Article
11. Rex DK, Cutler CS, Lemmel GT, et al. Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology. 1997; 112:24–28. PMID: 8978338.
Article
12. Tada M, Katoh S, Kohli Y, Kawai K. On the dye spraying method in colonofiberscopy. Endoscopy. 1977; 8:70–74. PMID: 67941.
Article
13. Mitooka H, Fujimori T, Ohno S, et al. Chromoscopy of the colon using indigo carmine dye with electrolyte lavage solution. Gastrointest Endosc. 1992; 38:373–374. PMID: 1607092.
14. Hurlstone DP, Cross SS, Slater R, Sanders DS, Brown S. Detecting diminutive colorectal lesions at colonoscopy: a randomised controlled trial of pan-colonic versus targeted chromoscopy. Gut. 2004; 53:376–380. PMID: 14960519.
Article
15. Westwood DA, Alexakis N, Connor SJ. Transparent cap-assisted colonoscopy versus standard adult colonoscopy: a systematic review and meta-analysis. Dis Colon Rectum. 2012; 55:218–225. PMID: 22228167.
16. Choi DH, Shin HK, Lee YC, et al. Efficacy of transparent cap-attached colonoscopy: does It improve the quality of colonoscopy? J Korean Soc Coloproctol. 2010; 26:116–122.
Article
17. Choi SW, Park HS, Lee JS, Hwang SY, Kwak SD, Choi SH. Efficacy of hood-cap assisted colonoscopy; comparison with conventional colonoscopy. Intest Res. 2012; 10:280–288.
Article
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