Intest Res.  2008 Dec;6(2):145-149.

A Case of Chronic Colonic Pseudo-obstruction with Visceral Myopathy

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. jooskim@snu.ac.kr
  • 2Department of General Surgery, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Chronic colonic pseudo-obstruction is a rare disease that results in colorectal dilatation without any obstructing lesions. Colonic dilatation does not usually cause colonic wall thickening and colonic visceral myopathy with muscular hypertrophy has not been reported in Korea. A 31-year-old female patient was transferred for treatment of refractory constipation accompanied by megacolon. She had suffered from recurrent attacks of severe abdominal pain with the sensation of a mass in the left lower quadrant. An abdominal CT revealed a large luminal dilatation of the sigmoid colon where massive stool was impacted. There was no obstructing lesion or luminal dilatation of the rectum. To relieve her refractory symptoms, a total colectomy with an ileorectal anastomosis was performed. Pathologic examination of the sigmoid colon revealed that the muscle layers were dysplastic and hypertrophied, and the innervations into the muscle fibers were markedly decreased. She was discharged without any intra-abdominal symptoms.

Keyword

Colonic Pseudo-Obstruction; Intestinal Pseudo-Obstruction; Constipation; Megacolon

MeSH Terms

Abdominal Pain
Adult
Colectomy
Colon
Colon, Sigmoid
Colonic Pseudo-Obstruction
Constipation
Dilatation
Female
Humans
Hypertrophy
Intestinal Pseudo-Obstruction
Korea
Megacolon
Muscles
Phenobarbital
Rare Diseases
Rectum
Sensation
Phenobarbital
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