J Korean Acad Child Adolesc Psychiatry.
2012 Oct;23(Suppl):S55-S65.
Pharmacotherapy of Comorbid Disruptive Behavioral Disorders in Children and Adolescents with ADHD
- Affiliations
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- 1Department of Psychiatry, Inje University College of Medicine, Pusan Paik Hospital, Busan, Korea.
- 2Department of Psychiatry, Inje University College of Medicine, Ilsan Paik Hospital, Goyang, Korea.
- 3Seoul Top Psychiatric Clinic, Seongnam, Korea.
- 4Department of Psychiatry, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea.
- 5Department of Psychiatry, Ajou University Hospital, Ajou University College of Medicine, Suwon, Korea.
- 6Seoul I Psychiatric Clinic, Suwon, Korea.
- 7Department of Psychiatry, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea.
- 8Department of Psychiatry, CHA Bundang Medical Center, School of Medicine, CHA University, Seongnam, Korea. cha99@cha.ac.kr
Abstract
- Disruptive behavioral disorders [oppositional defiant disorder (ODD) and conduct disorder (CD)] are common comorbid disorders in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). ODD/CD may be comorbid up to 60% of children and adolescents with ADHD. Comorbid ODD and CD symptoms can have a significant impact on the course and prognosis of patients with ADHD. Stimulant medications have shown effectiveness in treating both core ADHD symptoms and oppositional symptoms. Assessment and management of comorbid disruptive behavioral symptoms is an essential part in evaluation and treatment of ADHD patients. Further research is needed to investigate the efficacy and safety of various behavioral and medication regimens for ADHD, comorbid ODD and CD and to examine the relationships between ADHD, comorbid ODD and CD.