Chonnam Med J.  1999 Jun;35(2):303-308.

A Case of Cervical Pregnancy Treated by Intra-ovular Injection of Methotrexate

• Kim BR
• Kim YH
• Kim HJ
• Choi YS
• Kim SM
• Song TB

Abstract

Cervical pregnancy is one of most rare from of ectopic pregnancy in which the blastocyst implants within the cervical canal below the internal os of uterine cervix. Most cervical pregnancy result in early spontaneous abortion, complicated by severe hemorrhage from the eroded blood vessels within the cervix. Because of the fear of profuse hemorrhage, hysterectomy has been historically considered the standard therapy. However, a number of new therapies have been aimed at uterine preservation, conservative treatment is highly desirable for young women who want to be pregnancy in the future. Methotrexate has been utilized recently for the successful management of tubal, interstitial, and cervical ectopic gestations. We experienced one case of successful treatment of cervical pregnacy by direct local injection of methotrexate into gestational sac under the guidance of vaginal ultrasonogrom, so we report the case with a brief review of the concerned literatures.

Keyword

Cervical pregnancy; Methotrexate

MeSH Terms

Abortion, Spontaneous
Blastocyst
Blood Vessels
Cervix Uteri
Cytochrome P-450 CYP1A1
Female
Gestational Sac
Hemorrhage
Humans
Hysterectomy
Methotrexate*
Pregnancy*
Pregnancy, Ectopic
Cytochrome P-450 CYP1A1
Methotrexate