Chonnam Med J.  2012 Aug;48(2):128-129. 10.4068/cmj.2012.48.2.128.

Hypercalcemia in a Patient with Polycythemia Vera

Affiliations
  • 1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. skimw@chonnam.ac.kr
  • 2Department of Internal Medicine, Hankook Hospital, Mokpo, Korea.
  • 3Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.

Abstract

A 59-year-old female with diabetes mellitus presented with hypercalcemia and polycythemia. Her serum calcium and intact parathyroid hormone (iPTH) levels were increased, and Tc-99m sesta-MIBI scanning showed hot uptake in the lower portion of the left thyroid lobe. After parathyroidectomy, her calcium, iPTH, and polycythemia were normalized. In conclusion, the differential diagnosis of polycythemia and hypercalcemia should also include the possibility of a parathyroid tumor in addition to other neoplasms.

Keyword

Hypercalcemia; Polycythemia vera; Parathyroid tumor

MeSH Terms

Calcium
Diabetes Mellitus
Diagnosis, Differential
Female
Humans
Hypercalcemia
Middle Aged
Parathyroid Hormone
Parathyroidectomy
Polycythemia
Polycythemia Vera
Thyroid Gland
Calcium
Parathyroid Hormone

Figure

  • FIG. 1 Tc-99m sesta-MIBI scanning.

  • FIG. 2 Parathyroid adenoma. The tumor is hypercellular, homogeneous, and well vascularized. ×200.


Reference

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3. Pizzolito S, Barbone F, Rizzi C, Scott AC, Piemonte M, Beltrami CA. Parathyroid adenomas and malignant neoplasms: coincidence or etiological association? Adv Clin Path. 1997. 1:275–280.
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