Ann Dermatol.  2011 Feb;23(1):89-91. 10.5021/ad.2011.23.1.89.

A Case of Cutaneous Horn Originating from Keratoacanthoma

Affiliations
  • 1Department of Dermatology, Soonchunhyang University College of Medicine, Cheonan, Korea. dermsung@schmc.ac.kr
  • 2Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.

Abstract

Cutaneous horn is the clinical description of a hyperproliferation of compact keratin in response to a wide array of underlying benign and malignant pathologic changes. We report here on a case of cutaneous horn that originated from keratoacanthoma in a 76-year-old woman. Grossly, a 2.5x0.7 cm sized yellow-white colored scaly fungating mass from an erythematous nodule was observed on the right temporal area. Histopathologically, it was reported as keratoacanthoma with cutaneous horn. The lesion was totally excised after the diagnosis.

Keyword

Cutaneous horn; Keratoacanthoma

MeSH Terms

Aged
Animals
Female
Horns
Humans
Keratins
Keratoacanthoma
Keratins

Figure

  • Fig. 1 A 3×3 cm sized erythematous patch with a central 1×1 cm sized hypertrophic nodule on the right temple. A yellowish-white colored cylindrical horn with a base diameter of 0.7 cm and a height of 2.7 cm arose from the central nodule.

  • Fig. 2 Lesion of the cutaneous horn. This was a 2.7×0.7 cm sized hyperkeratotic mass with focal keratin pearl (H&E, ×10).

  • Fig. 3 Lesion of keratoacanthoma. (A) Note the central hyperkeratotic plug with surrounding epidermis. (B) The lesion is well demarcated and it does not extend downward. In the center, an eosinophilic glassy appearance is seen as a consequence of keratinization (A: H&E, ×40, B: H&E, ×100).


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