Ann Dermatol.  2015 Aug;27(4):465-466. 10.5021/ad.2015.27.4.465.

Cefaclor-Induced Generalized Fixed Drug Eruption

• Kim EJ
• Kim JE
• Ro YS
• Ko JY

• KMID: 2171513
• DOI: http://doi.org/10.5021/ad.2015.27.4.465

Abstract

No abstract available.

MeSH Terms

Drug Eruptions*

Figure

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  Fig. 1 (A) Generalized brownish hyperpigmented annular patches over the whole body after taking cefaclor, ioxoprofen, and streptokinase/streptodornase. (B) Development of new lesions and darkening of existing lesions after taking cefaclor 250 mg.

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  Fig. 2 Skin biopsy specimen showing edematous degeneration of the basal membrane of the epidermis, pigment incontinence, and superficial perivascular lymphocytic infiltration (H&E, ×200).

Reference

1. Kim YS, Kang HJ, Hahm JH. A case of generalized fixed drug eruption due to mefenamic acid. Ann Dermatol. 1996; 8:211–214.

2. Nail S, Sandra K. Cutaneous reactions to drugs. In : Fitzpatrick T, Goldsmith L, editors. Fitzpatrick's dermatology in general medicine. 8th ed. New York: McGrawHill Medical;2012. p. 454–455.

3. Andrade P, Brinca A, Gonçalo M. Patch testing in fixed drug eruptions--a 20-year review. Contact Dermatitis. 2011; 65:195–201.