Ann Dermatol.  2015 Oct;27(5):563-577. 10.5021/ad.2015.27.5.563.

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Affiliations
  • 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 2Department of Dermatology, Seoul Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
  • 3Department of Dermatology, Kyung Hee University College of Medicine, Seoul, Korea.
  • 4Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
  • 5Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
  • 6Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
  • 7Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 8Department of Dermatology, SA Dermatology Clinic, Daejeon, Korea.
  • 9Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
  • 10Department of Dermatology, Pusan National University School of Medicine, Busan, Korea.
  • 11Department of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
  • 12Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
  • 13Department of Dermatology, Chungnam National University College of Medicine, Daejeon, Korea.
  • 14Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
  • 15Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
  • 16Department of Dermatology, Gachon University Gil Medical Center, Incheon, Korea. jyroh1@gilhospital.com

Abstract

BACKGROUND
Since the treatment guidelines for atopic dermatitis (AD) were released by the Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been several advances in AD management.
OBJECTIVE
We aimed to establish updated evidence- and experience-based treatment guidelines for Korean AD.
METHODS
We collected a database of references from relevant systematic AD reviews and guidelines regarding general AD management such as bathing and skin care, avoidance of exacerbating factors, education and psychosocial support, and the use of moisturizers and topical anti-inflammatory and antipruritic drugs. Evidence for each statement was graded and the strength of the recommendation for each statement classified. Thirty-nine KADA council members participated in three rounds of voting to establish an expert consensus of recommendations.
RESULTS
Basic AD treatment includes proper bathing and skin care, avoidance of exacerbating factors, proper education and psychosocial support, and use of moisturizers. The regular use of moisturizer has a steroid-sparing effect and reduces relapse episodes. The short- and long-term use of topical corticosteroids and calcineurin inhibitors improves AD symptoms and should be encouraged to use in an active and proactive treatment. Wet-wrap therapy can be used for rapid recovery of acute exacerbation. Topical antipruritic drugs cannot be recommended for the treatment of AD.
CONCLUSION
This report provides up-to-date evidence- and experience-based treatment guidelines for AD regarding general management and topical treatment. In addition, the average agreement scores obtained by a panel of experts based on the Korean healthcare system and patient adherence are presented.

Keyword

Administration; topical; Guideline; Therapeutics

MeSH Terms

Adrenal Cortex Hormones
Antipruritics
Baths
Calcineurin
Consensus*
Delivery of Health Care
Dermatitis, Atopic*
Education
Korea*
Patient Compliance
Politics
Recurrence
Skin Care
Adrenal Cortex Hormones
Antipruritics
Calcineurin

Figure

  • Fig. 1 The fingertip unit (FTU) method is used in to determine the amount of topical corticosteroids (TCS) or calcineurin inhibitors to apply. The amount from the distal skin crease to the tip of an adult patient's index finger is equivalent to approximately 0.5 g TCS. 1 FTU generally covers the surface area of two palms.


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Yonsei Med J. 2019;60(7):694-699.    doi: 10.3349/ymj.2019.60.7.694.

Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis
Min Seok Hur, Yong Beom Choe, Kyu Joong Ahn, Yang Won Lee
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Current research status of pediatric atopic dermatitis in Korea
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Allergy Asthma Respir Dis. 2018;6(Suppl 1):S40-S43.    doi: 10.4168/aard.2018.6.S1.S40.

Wet wrap therapy in atopic dermatitis
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Allergy Asthma Respir Dis. 2019;7(1):1-2.    doi: 10.4168/aard.2019.7.1.1.

A clinician's reference guide for the management of atopic dermatitis in Asians
Steven Chow, Chew Swee Seow, Maria Victoria Dizon, Kiran Godse, Henry Foong, Vicheth Chan, Tran Hau Khang, Leihong Xiang, Syarief Hidayat, M. Yulianto Listiawan, Danang Triwahyudi, Srie Prihianti Gondokaryono, Endang Sutedja, Inne Arline Diana, Oki Suwarsa, Hartati Purbo Dharmadji, Agnes Sri Siswati, Retno Danarti, Retno Soebaryo, Windy Keumala Budianti,
Asia Pac Allergy. 2018;8(4):.    doi: 10.5415/apallergy.2018.8.e41.

Current Management of Moderate-to-Severe Atopic Dermatitis: A Survey of Allergists, Pediatric Allergists and Dermatologists in Korea
Hye Yung Yum, Hyun Hee Kim, Hyun Jung Kim, Woo Kyung Kim, So-Yeon Lee, Kapsok Li, Dong Hun Lee,
Allergy Asthma Immunol Res. 2018;10(3):253-259.    doi: 10.4168/aair.2018.10.3.253.

The efficacy of wet wrap therapy in children with atopic dermatitis in a single center
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