Ewha Med J.  2015 Mar;38(1):14-21. 10.12771/emj.2015.38.1.14.

Comparison of Anaphylaxis and Angioedema with Oral Mucosal Involvement in a Single Pediatric Emergency Department

• Keum HS
• Lee DK
• Cho SJ
• Hong YM
• Kwon JH

• KMID: 2171324
• DOI: http://doi.org/10.12771/emj.2015.38.1.14

Abstract

OBJECTIVES
We aimed to compare and distinguish the characteristics of anaphylaxis and angioedema, especially with oral mucosal involvement and treatment of patients who visited the Pediatric Emergency Department.
METHODS
We retrospectively analyzed patients under age 18-year-old who were diagnosed with anaphylaxis and angioedema with oral mucosal involvement and treated with epinephrine from May 2008 to May 2013 in a single Pediatric Emergency Department in Seoul, Korea. We evaluated their past history, possible triggering causes, symptoms, vital signs and treatment and discharge with education.
RESULTS
During the study period the total cases of anaphylaxis were 79 and angioedema with oral mucosal involvement were 218. The age of patients with anaphylaxis was significantly higher (6.6+/-4.9 years vs. 4.1+/-3.3 years). The heart rate relative to age was significantly higher in the anaphylaxis group (49.4% vs. 36.2%). After discharge from the Emergency Center, 3.8% of anaphylaxis patients were prescribed an epinephrine injection. Education to avoid the triggering factor was provided in 32.9% of anaphylaxis group and 17.4% in the angioedema group.
CONCLUSION
Besides blood pressure, we should pay attention to the heart rate in pediatric patients with severe allergic reactions. More active follow-up of anaphylaxis and angioedema with oral mucosal involvement is needed to educate parents and prescribe emergency medication.

Keyword

Anaphylaxis; Angioedema; Child

MeSH Terms

Adolescent
Anaphylaxis*
Angioedema*
Blood Pressure
Child
Education
Emergencies
Emergency Service, Hospital*
Epinephrine
Heart Rate
Humans
Hypersensitivity
Korea
Parents
Retrospective Studies
Seoul
Vital Signs
Epinephrine

Figure

• 

  Fig. 1 The proportion of patients for suspected foods of anaphylaxis and angioedema.

• 

  Fig. 2 The proportion of clinical manifestations of patients with anaphylaxis.

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