Ewha Med J.  2014 Dec;37(Suppl):S41-S43. 10.12771/emj.2014.37.S.S41.

Syndrome of Inappropriate Secretion of Antidiuretic Hormone after Lung Transplantation

• Joo YS
• Yoon CY
• Han SG
• Lee E
• Han IM
• Woo MS
• Park SH
• Yoo TH

• KMID: 2171311
• DOI: http://doi.org/10.12771/emj.2014.37.S.S41

Abstract

A 54-year-old man was diagnosed as syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 7 days after lung transplantation, whereas the preoperative serum sodium level was normal. Hypertonic saline infusion with furosemide did not improve hyponatremia, however, tolvaptan corrected his serum sodium levels from 123 mEq/L to 131 mEq/L. Seven days after maintenance of tolvaptan, this drug was discontinued and hyponatremia did not occur. Herein, we report a case of SIADH after lung transplantation treated with tolvaptan.

Keyword

Lung transplantation; Inappropriate ADH syndrome; Hyponatremia

MeSH Terms

Furosemide
Humans
Hyponatremia
Inappropriate ADH Syndrome
Lung Transplantation*
Middle Aged
Sodium
Furosemide
Sodium

Figure

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  Fig. 1 Chest X-ray taken before lung transplantation (LT) (A) and 7 days after LT (B). Chest X-ray shows no signs of pulmonary edema except for postoperative changes.

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  Fig. 2 Changes in the serum sodium levels during hospitalization. Hypertonic saline was administrated for first 3 days and replaced to tolvaptan. Oral tolvaptan was maintained for 9 days and he was discharged on 23th day of lung transplantation.

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