Change in Vertebral Body Marrow in Degeberative Lumbar Disc Disease

Koh, Young Do; Kim, Jong Oh

Abstract

OBJECTIVES
In order to evaluate clinical significance of MR signal change within vertebral body marrow, we investigated the relationship between signal change of marrow and duration of low back pain, hight of disc, segmental hypermobility, disc degeneration and degree of disc herniation.
METHODS
We reviewed retrospectively simple radiograph, flexion-extension dynamic radiograph and MR images of the lumber spines(L3-S1) of 100 patients, who underwent discectomy at Ewha Womans University Mokdong Hospital from September 1993 to October 1996.
RESULTS
1) There were Modic type 2 changes in 36 patients of 100 patients(36%) and in 52 segments of 300 segments(17.3%). 2) Average was older in the group with signal change in marrow than in that without signal change. 3) Signal change of vertebral body marrow was not significantly related to duration of low back pain. 4) Decreased disc heght was more frequently found in segments with signal change in marrow than in those without signal chagne. 5) Modic type 2 changes was not related to lumbar segmental hypermobility. 6) Degeneration of disc was more frequently found in segments with signal change in marrow than in those without signal change. 7) Signal change of vertebral body marrow was not directly related to degree of disc herniation.
CONCLUSION
Signal change of vertebral body marrow in MRI was significantly related to age, disc height and degree of disc degeneration, and it suggests that the marrow change can be induced by response of vertebral body to the changed mechanical environment, which is due to long-standing disc degeneration.