- Outcome of Aflibercept-Bevacizumab Alternate Dosing in Neovascular Age-related Macular Degeneration with Limited Response to Aflibercept
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Shin D, Kim JH
- KMID: 2530552
- J Korean Ophthalmol Soc.
- 2022 Jun;63(6):526-534.
- doi: 10.3341/jkos.2022.63.6.526
Purpose: To investigate the efficacy of aflibercept-bevacizumab alternate dosing (AD) in neovascular age-related macular degeneration (AMD) with a limited response to bimonthly aflibercept injections. Methods: This retrospective study included patients given... -
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- A Case of Pathologically Confirmed Corticobasal Degeneration Initially Presenting as Progressive Supranuclear Palsy Syndrome
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Chung EJ, Cho HJ, Jang W, Hur DY, Kim YS, Lee KH, Kim SJ
- KMID: 2530421
- J Korean Med Sci.
- 2022 Jun;37(22):e183.
- doi: 10.3346/jkms.2022.37.e183
Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) overlap clinically with parkinsonism or extrapyramidal signs and pathologically with tauopathy. Asymmetric parkinsonism and cortical dysfunctions are classical features of CBD. However,... -
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- Diurnal Variation in Hydration of the Cervical Intervertebral Disc Assessed Using T2 Mapping of Magnetic Resonance Imaging
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Liu C, Wang J, Hou B, Li Y, Morelli JN, Zhang P, Ran J, Li X
- KMID: 2530358
- Korean J Radiol.
- 2022 Jun;23(6):638-648.
- doi: 10.3348/kjr.2021.0950
Objective: The study aimed to investigate the diurnal variation in cervical disc hydration and its relationship with cervical degeneration. Materials and Methods: C3–C7 discs of 86 prospectively enrolled participants (37 males,... -
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- Factors Associated with Macular Staphyloma Area on Ultra-widefield Fundus Images
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Zhang X, Pazo EE, Zhang A, Yang L, Dai G, Wu X, Xia Y, Meshi A, He W, Lin T
- KMID: 2530587
- Korean J Ophthalmol.
- 2022 Jun;36(3):210-217.
- doi: 10.3341/kjo.2021.0081
Purpose: To assess the feasibility of applying ultra-widefield fundus (UWF) images for macular staphyloma area (MSA) measurement and investigate the associated factors with MSA. Methods: This is a retrospective study. MSA... -
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- Transcriptome Analysis of Long-Term Exposure to Blue Light in Retinal Pigment Epithelial Cells
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Jin HL, Jeong KW
- KMID: 2529895
- Biomol Ther.
- 2022 May;30(3):291-297.
- doi: 10.4062/biomolther.2021.155
Dry age-related macular degeneration (AMD) is a type of progressive blindness that is primarily due to dysfunction and the loss of retinal pigment epithelium (RPE). The accumulation of N-retinylidene-N-retinylethanolamine (A2E),... -
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- Aqueous Humor Cytokine Levels and Choroidal Thicknesses of Patients with Age‐related Macular Degeneration and Pachychoroid Neovasculopathy
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Kong JH, Kim YD, Park SP, Kim Y
- KMID: 2528328
- J Korean Ophthalmol Soc.
- 2022 Apr;63(4):361-369.
- doi: 10.3341/jkos.2022.63.4.361
Purpose: We sought correlations between the subfoveal choroidal thickness (SCT) and changes in the levels of aqueous humor cytokines before and after anti‐vascular endothelial growth factor (anti‐VEGF) treatment of patients... -
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- Chemokine Receptor Profiles of T Cells in Patients with Age-Related Macular Degeneration
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Choi YJ, Lim D, Byeon SH, Shin EC, Chung H
- KMID: 2527517
- Yonsei Med J.
- 2022 Apr;63(4):357-364.
- doi: 10.3349/ymj.2022.63.4.357
Purpose: To evaluate the expression of multiple chemokine receptors in peripheral blood T cells from patients with age-related macular degeneration (AMD). Materials and Methods: Peripheral blood mononuclear cells and/or aqueous humor... -
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- Vertebral Endplate Changes Correlate with Presence of Cartilaginous Endplate in the Herniated Disc Tissue: Factor Predicting Failure of Conservative Treatment
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Latif R, Imran S, Ahmad I, Ilyas MS, Aziz A, Zehra U
- KMID: 2529527
- Asian Spine J.
- 2022 Apr;16(2):212-220.
- doi: 10.31616/asj.2021.0106
Study Design: Cross-sectional comparative. Purpose: To characterize the scores of disc degeneration, inflammation, and nerve density in herniated disc samples and associate findings with the presence of vertebral endplate (VEP) changes... -
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- Paraneoplastic Cerebellar Degeneration Presented as Acute Vertigo
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Kim SH
- KMID: 2527424
- Res Vestib Sci.
- 2022 Mar;21(1):24-27.
- doi: 10.21790/rvs.2022.21.1.24
Paraneoplastic cerebellar degeneration is a rare neurological manifestation of nonmetastatic malignancy. Its usual manifestation is subacute to chronic dizziness, gait ataxia, and dysarthria. There have been only a few cases... -
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- Current Knowledge and Future Therapeutic Prospects in Symptomatic Intervertebral Disc Degeneration
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Kim JH, Ham CH, Kwon WK
- KMID: 2526552
- Yonsei Med J.
- 2022 Mar;63(3):199-210.
- doi: 10.3349/ymj.2022.63.3.199
Intervertebral disc (IVD) degeneration is the main source of intractable lower back pain, and symptomatic IVD degeneration could be due to different degeneration mechanisms. In this article, we describe the... -
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- Histological Changes of Cervical Disc Tissue in Patients with Degenerative Ossification
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Xiong Y, Yang YL, Gao YS, Wang XM, Yu X
- KMID: 2527175
- J Korean Neurosurg Soc.
- 2022 Mar;65(2):186-195.
- doi: 10.3340/jkns.2021.0082
Objective : To explore the histological feature of the cervical disc degeneration in patients with degenerative ossification (DO) and its potential mechanisms. Methods : A total of 96 surgical segments, from... -
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- Protocatechuic acid impacts rotator cuff healing and reduces fatty degeneration in a chronic rotator cuff tear model in rats
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Seo SJ, Park JY, Park HJ, Hwang JT
- KMID: 2527933
- Clin Should Elbow.
- 2022 Mar;25(1):5-14.
- doi: 10.5397/cise.2021.00395
Background: The purpose of this study was to verify the effect of protocatechuic acid (PCA) on tendon healing and fatty degeneration in a chronic rotator cuff model. Methods: Twenty-eight Sprague-Dawley... -
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- Intraocular Cytokine Changes in Patients with Polypoidal Choroidal Vasculopathy Treated with Ranibizumab
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Choi Y, Kim SH, Choi SK, Lee JJ, Lee SM, Kwon HJ, Park SW, Lee JE, Byon IS
- KMID: 2526506
- J Korean Ophthalmol Soc.
- 2022 Feb;63(2):166-174.
- doi: 10.3341/jkos.2022.63.2.166
Purpose: To investigate the changes in intraocular cytokines after ranibizumab treatment in patients with polypoidal choroidal vasculopathy (PCV). Methods: This multicenter, prospective study enrolled patients with PCV treated with three monthly... -
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- Preventive and Restorative Responses of Broccoli Sprouts on Biomechanical Structures, Histomorphometric, and Gene Expression Levels of Degenerated Intervertebral Disc in Rabbit Model
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Ogunlade B, Ogunlade B, Fidelis OP, Fidelis OP, Adelakun SA, Adelakun SA
- KMID: 2526584
- Asian Spine J.
- 2022 Feb;16(1):92-98.
- doi: 10.31616/asj.2020.0479
Study Design: Symptomatic disk degeneration is characterized by early pathological changes in the morphological, biochemical, and biomechanical properties of the intervertebral disc (IVD). Several methods that can be used to... -
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- Co-Existence of Anterior and Posterior Column Lesions in Patients with Subacute Combined Degeneration
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Choi K, Moon Y, Oh J
- KMID: 2523953
- Korean J Neuromuscul Disord.
- 2021 Dec;13(2):44-47.
- doi: 10.46518/kjnmd.2021.13.2.44
Subacute combined degeneration (SCD) of the spinal cord, which is a result of vitamin B12 deficiency, may cause irreversible neurological deficits. The lesion in the spinal cord is typically localized... -
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- Trans-Synaptic Degeneration of Peripheral Motor Axons from Metastatic Brain Tumors: Electrophysiological Findings in Two Cases
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Won JH, Chae HJ, Kim K, Hyun SE
- KMID: 2526157
- J Electrodiagn Neuromuscul Dis.
- 2021 Dec;23(3):82-88.
- doi: 10.18214/jend.2021.00066
Denervation potentials obtained during electromyography (EMG) are usually considered as evidence of axonal degeneration in the peripheral nervous system (PNS). However, they may also appear when only central nervous system... -
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- Exhibiting Residual Subretinal Fluid after High Myopic Macular Hole Retinal Detachment Surgery
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Kim SJ, Lee JJ, Byon IS, Lee JE, Park SW
- KMID: 2523323
- J Korean Ophthalmol Soc.
- 2021 Dec;62(12):1672-1678.
- doi: 10.3341/jkos.2021.62.12.1672
Purpose: To report a case of poor visual prognosis complicated by residual subretinal fluid after use of the internal limiting membrane flap technique to treat macular hole retinal detachment in... -
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- Correlation between Topographic Progression of Geographic Atrophy and Visual Acuity Changes
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You JI, Kim DG, Yu SY, Kim ES, Kim K
- KMID: 2523037
- Korean J Ophthalmol.
- 2021 Dec;35(6):448-454.
- doi: 10.3341/kjo.2021.0037
Purpose: To analyze topographic progression of geographic atrophy with different concentric circles centered on the fovea in correlation with decrease of visual acuity. Methods: We retrospectively analyzed 36 eyes of 26... -
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- Polydeoxyribonucleotide and Polynucleotide Improve Tendon Healing and Decrease Fatty Degeneration in a Rat Cuff Repair Model
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Hwang JT, Lee SS, Han SH, Sherchan B, Panakkal JJ
- KMID: 2522575
- Tissue Eng Regen Med.
- 2021 Dec;18(6):1009-1020.
- doi: 10.1007/s13770-021-00378-5
BACKGROUND: After surgical repair of chronic rotator cuff tears, healing of the repaired tendons often fails and is accompanied by high-level fatty degeneration. Our purpose was to explore the effects... -
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- Study of Patients with Bilateral Knee Osteoarthritis Undergoing Total Knee Replacement Procedure with Coexisting Lumbar Spondylosis Symptoms
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Londhe SB, Shah RV, Patwardhan M, Doshi AP, Londhe SS, Subhedar K, Kundnani V, Patel J
- KMID: 2523383
- Asian Spine J.
- 2021 Dec;15(6):825-830.
- doi: 10.31616/asj.2020.0279
Study Design: This is a prospective cohort study involving patients who were followed for 2 years after total knee replacement (TKR) to determine changes in lumbar spine and knee symptoms. Purpose:... -
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