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Biochemical Factors of Intervertebral Disc Degeneration: Implications for Disc Regeneration

Moon SH

Intervertebral disc degeneration is main cause of various spinal degenerative conditions, and results in a significant socio-economic burden and morbidity to those affected. Intervertebral disc degeneration is a multifactorial process...
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Spontaneous Total Resolution of Severe Lumbar Disc Herniation

Kaliya-Perumal AK, Oh JY

No abstract available.
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Correlation between Bone Mineral Density and Interverterbral Disc Degeneration

Kim YG, Jung YS, Kim SS, Choi HJ, Hong JH, Chon JS, Kim HS, Ahn KH

  • KMID: 2323448
  • J Korean Acad Rehabil Med.
  • 2000 Jun;24(3):557-562.
OBJECTIVE: To examine the correlation between bone mineral density and intervertebral disc degeneration through retrospective study. METHOD: Bone mineral density (BMD) and Magnetic resonance (MR) image of lumbar spine from 61...
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Changes of Posterior Bulging of the Lumbar Intervertebral Discs with Flexion and Extension in Central Disc Bulges and Disc Degeneration

Lee SU, Fredericson M

  • KMID: 2136711
  • J Korean Acad Rehabil Med.
  • 2001 Apr;25(2):302-307.
OBJECTIVE: To determine the changes of posterior bulging of the lumbar intervertebral discs with flexion and extension movement of the spine in patients with central disc bulges or disc degeneration. METHOD:...
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Pathophysiology of Degenerative Disc Disease

Choi YS

The intervertebral disc is characterized by a tension-resisting annulus fibrosus and a compression-resisting nucleus pulposus composed largely of proteoglycan. The most important function of the annulus and nucleus is to...
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Lumbar Disc Degeneration and Segmental Instability: A Comparison of Magnetic Resonance Images and Plain Radiographs

Park SR, Kim HS, Kang JS, Lee WH, Lee JH, Lee TJ

  • KMID: 2209832
  • J Korean Soc Spine Surg.
  • 1997 Nov;4(2):281-290.
SUMMARY OF LITERATURE REVIEW: Many authors haute described the association between lumbar disc degeneration and segmental instability but it has not been delineated in detail. OBJECTIVES: To compare the MRI assessment...
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Immuno-expression of Type IV Collagen in the Intervertebral Disc

Jeon CH, Moon JH, Kang YH

STUDY DESIGN: In vitro studies using human intervertebral disc for the localization of the type IV collagen. OBJECTIVE: 1) To study the distribution pattern and immunoexpression of type 4 collagen in...
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The Influence of the Various Configurations of Lower Lumbar and Lumbosacral Spine on the Disc Degeneration: Multifactorial Analysis

Lee CS, Chung SS, Lee SG, Ji MS, Jeong YK, Kim SE

  • KMID: 2105462
  • J Korean Orthop Assoc.
  • 1998 Dec;33(7):1640-1647.
There are some controversies on the mechanism of the lumbar disc degeneration and disc prolapse. But,it is clear that many factors are related to the disc degeneration. Configurations of the...
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Indirect decompression as a minimally invasive spine surgery

Oh SH

  • KMID: 2053710
  • Hanyang Med Rev.
  • 2008 Feb;28(1):45-49.
The purpose of this study is to introduce the various methods of indirect decompression of minimally invasive procedures available for treatment of lumbar spine surgery. A review of the literature,...
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Lumbar Total Disc Replacement

Ryu KS, Park CK

  • KMID: 1465929
  • Korean J Spine.
  • 2009 Dec;6(4):251-259.
In surgical treatments of degenerative lumbar disc disease, arthrodesis is well known to be a gold standard; however various disadvantages related to elimination of the segmental motion and the procedures...
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The Effect of Disc Degeneration in Osteoporotic Vertebral Fracture

Lee KS

  • KMID: 2097723
  • J Korean Soc Spine Surg.
  • 2000 Dec;7(4):558-564.
STUDY DESIGN: Radiographic findings of vertebral fracture and disc degeneration in osteoporotic spine were observed OBJECTIVES: We investigated the relationship between osteoporotic fractures of vertebral body and disc degeneration. MATERIALS AND...
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Vitamin D Receptor Gene, Matrix Metalloproteinase 3 Polymorphisms and the Risk of Intervertebral Disc Degeneration Susceptibility: Meta-Analysis

Nong L, Huang Y, Zhao S, Xu N

Several studies have evaluated the association between vitamin D receptor, matrix metalloproteinase 3 (MMP-3) polymorphisms and the risk of intervertebral disc degeneration susceptibility. The findings were inconsistent. This meta-analysis aimed...
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The Production of Interleukin - 1 and Stromelysin in the Cultured Intervertebral Disc Cells of Rabbit

Kim DJ

  • KMID: 2336071
  • J Korean Orthop Assoc.
  • 1998 Jun;33(3):858-867.
The cells of anulus fibrosus(AF) and nucleus pulposus(NP) of intervertebral disc are thought to be different in their cell components and in their roles during degeneration. The purpose of this...
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Development of an Intervertebral Disc Degeneration Model using Newzealand White Rabbits

So K, Choi Y, Yoon D, Ryu J, Johnstone , Yoo JU

STUDY DESIGN: An experimental animal study. OBJECTIVES: To create a more appropriate disc degeneration model which shows how Interleukin 1alpha may induce the activation of metalloproteinases within the nucleus pulposus. SUMMARY OF...
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Effects of Growth Hormone on the Degenerative Changes in the Intervertebral Disc of Rabbits

Park YJ, Han SH, Hwang IK

  • KMID: 1993591
  • Kosin Med J.
  • 2011 Dec;26(2):135-143.
OBJECTIVES: Growth hormone is expected to delay the degenerative changes of the intervertebral disc and affect the initial recovery process of cartilage injury, but these effects are still open to...
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High Glucose Accelerates Autophagy in Adult Rat Intervertebral Disc Cells

Kong CG, Park JB, Kim MS, Park EY

STUDY DESIGN: In vitro cell culture. PURPOSE: The purpose of this study was to investigate the effect of high glucose on autophagy in adult rat intervertebral disc cells. OVERVIEW OF LITERATURE: Diabetes...
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Use of Annular Closure Device (Barricaid(R)) for Preventing Lumbar Disc Reherniation: One-Year Results of Three Cases

Hahn BS, Ji GY, Moon B, Shin DA, Ha Y, Kim KN, Yoon DH

Although lumbar discectomy is an effective treatment for lumbar disc herniation, complications exist, including postoperative disc height loss, facet joint degeneration, and recurrent disc herniation. To solve these problems, annular...
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The Classification of Lumbar Interspinous Ligament in Relation to Herniated Intervertebral Disc and Spinal Degeneration of Korean

Kim JC, Jang KU, Kim SS, Park DS

  • KMID: 2136619
  • J Korean Acad Rehabil Med.
  • 2002 Aug;26(4):449-455.
OBJECTIVE: To classify the findings of magnetic resonance imaging of the lumbar interspinous ligaments in relation to the lumbar disc herniation, disc degeneration, and lordosis. METHOD: The subjects were 45 herniated...
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MRI Assessments of Adjacent Disc Degeneration Following Lumbar Fusion

Chung NS, Jeon CH, Chung GY, Park JW

STUDY DESIGN: Retrospective case-control study OBJECTIVE: To use MRI to assess intervertebral disc degeneration at adjacent levels after spinal fusion and after discectomy. SUMMARY OF LITERATURE REVIEW: Degeneration of adjacent intervertebral discs...
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The Obturator Guiding Technique in Percutaneous Endoscopic Lumbar Discectomy

Han IH, Choi BK, Cho WH, Nam KH

In conventional percutaneous disc surgery, introducing instruments into disc space starts by inserting a guide needle into the triangular working zone. However, landing the guide needle tip on the annular...
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