Infect Chemother.  2010 Jun;42(3):190-193. 10.3947/ic.2010.42.3.190.

A Case of Citrobacter braakii Sepsis Complicated with Hepatocellular Carcinoma

• Lee HM
• Bae SH
• Lee SN
• Lee JW
• Shin AY
• Yu SY
• Lee SY
• Youn MH
• Han SY
• Han NI
• Lee YS
• Yoo JH

• KMID: 2170309
• DOI: http://doi.org/10.3947/ic.2010.42.3.190

Abstract

Citrobacter species is a gram-negative bacilli that can cause opportunistic infections in immunocompromised hosts. Citrobacter braakii refers to the genomospecies 6 of the Citrobacter freundii complex. There are no detailed studies on infections caused by this newly identified specific genetic species in Korea. We herein report a case of a patient with hepatocellular carcinoma who, after undergoing transcatheter arterial chemoembolization, developed biloma which later progressed to C.braakii sepsis and did not respond to treatment. To our knowledge, this is the first reported case in Korea on C. braakii infection resulting in septic shock in a patient with malignancy in Korea.

Keyword

Citrobacter braakii; Biloma; Sepsis

MeSH Terms

Carcinoma, Hepatocellular
Citrobacter
Citrobacter freundii
Humans
Immunocompromised Host
Korea
Opportunistic Infections
Sepsis
Shock, Septic

Figure

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  Figure 1 Abdomen CT scan shows viable tumor around previous lipiodolized mass in the right hepatic lobe. A 6×4 cm-sized biloma (arrow) is noted around the hepatoduodenal ligament, suggesting bile duct necrosis with perforation.

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  Figure 2 Newly developed 3.5 cm-sized abscess (arrow head) is observed in the right hepatic lobe on follow-up abdominal CT scan. The biloma around the hepatoduodenal ligament has decreased in size.

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