J Biomed Res.  2014 Mar;15(1):36-39.

Male pseudohermaphroditism in a Maltese/poodle mixed dog

• Jang SJ
• Kim YJ
• Kim G
• Choi SH

Abstract

Male pseudohermaphroditism is not commonly reported in veterinary medicine. Here, a 3-year-old Maltese/poodle mixed dog presented with malformed external genitalia and episodic hematuria. Inspection and palpation of the external genitals showed a malformed penis, shortened prepuce, external urethral orifice, and cryptorchidism. There was no urethral meatus at the tip of the penis. The urethral opening was situated between the prepuce and the penis. The anterior half of the prepuce was absent, and the penis was free and exposed to both trauma and licking. Plain radiographic examination showed absence of an os penis in the penis. A double-contrast cystograph showed the suspected uterus as well as the cystic calculi. A hypoechoic space was seen at the dorsal portion of the urinary bladder. The space was suspected to be the uterus. A sagital ultrasonograph showed cystic calculi in the urinary bladder. During surgery to remove cystic calculi, hypoplastic testes as well as the uterus were observed. Histological examination of the testes showed the seminiferous tubules and interstitial cells. The sertoli cells and spermatogonia were adjacent to the basement membrane. No evidence of spermatogenesis was found. Striated squamous epithelial cells and smooth muscle cells were found in the uterus. This dog had vestigial oviducts as well as a uterus with male-appearing external genitals.

Keyword

dog; genital; pseudohermaphroditism; testis; uterus

MeSH Terms

46, XY Disorders of Sex Development*
Animals
Basement Membrane
Calculi
Child, Preschool
Cryptorchidism
Disorders of Sex Development
Dogs*
Epithelial Cells
Genitalia
Hematuria
Humans
Male
Myocytes, Smooth Muscle
Oviducts
Palpation
Penis
Seminiferous Tubules
Sertoli Cells
Spermatogenesis
Spermatogonia
Testis
Urinary Bladder
Uterus
Veterinary Medicine