- Management of Anabolic Steroid-Induced Infertility: Novel Strategies for Fertility Maintenance and Recovery
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Tatem AJ, Beilan J, Kovac JR, Lipshultz
- KMID: 2471821
- World J Mens Health.
- 2020 Apr;38(2):141-150.
- doi: 10.5534/wjmh.190002
There is often inherent conflict in the overlapping fields of male fertility and andrology. While the goal of all male fertility specialists is to facilitate and preserve biologic paternity, many... -
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- Proteomic Signatures in Spermatozoa Reveal the Role of Paternal Factors in Recurrent Pregnancy Loss
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Mohanty G, Jena SR, Nayak J, Kar S, Samanta L
- KMID: 2465415
- World J Mens Health.
- 2020 Jan;38(1):103-114.
- doi: 10.5534/wjmh.190034
PURPOSE: To identify the paternal factors responsible for aberrant embryo development leading to loss of foetus in recurrent pregnancy loss (RPL) through proteomic analysis of ejaculated spermatozoa. MATERIALS AND METHODS: This... -
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- Microtubular Dysfunction and Male Infertility
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Gunes S, Sengupta P, Henkel R, Alguraigari A, Sinigaglia MM, Kayal M, Joumah A, Agarwal A
- KMID: 2465406
- World J Mens Health.
- 2020 Jan;38(1):9-23.
- doi: 10.5534/wjmh.180066
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of... -
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- Investigation of the association of idiopathic male infertility with polymorphisms in the methionine synthase (MTR) gene
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Tanoomand , Hajibemani A, Abouhamzeh B
- KMID: 2458497
- Clin Exp Reprod Med.
- 2019 Sep;46(3):107-111.
- doi: 10.5653/cerm.2018.00423
OBJECTIVE: Spermatogenesis is a complex process that is regulated by a number of genes, some of which are involved in folate-dependent 1-carbon metabolism. Methionine synthase (encoded by MTR) is a... -
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- Protective Effect of All-Trans Retinoic Acid in Cisplatin-Induced Testicular Damage in Rats
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Yucel C, Arslan FD, Ekmekci S, Ulker V, Kisa E, Erdogan Yucel E, Ucar M, Ilbey YO, Celik O, Basok BI, Kozacioglu Z
- KMID: 2443241
- World J Mens Health.
- 2019 May;37(2):249-256.
- doi: 10.5534/wjmh.180105
PURPOSE: To investigate the effects of all-trans retinoic acid (ATRA) in cisplatin (CP)-induced testicular damage in rats. MATERIALS AND METHODS: Twenty-eight male Wistar rats were divided into four groups: Control, ATRA... -
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- Recovery of Spermatogenesis Following Cancer Treatment with Cytotoxic Chemotherapy and Radiotherapy
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Okada K, Fujisawa M
- KMID: 2443232
- World J Mens Health.
- 2019 May;37(2):166-174.
- doi: 10.5534/wjmh.180043
The survival rates of boys and men with cancer have increased due to advances in cancer treatments; however, maintenance of quality of life, including fertility preservation, remains a major issue.... -
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- Novel method of histopathological analysis after testicular sperm extraction in patients with nonobstructive and obstructive azoospermia
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Cito G, Coccia ME, Picone R, Nesi G, Cocci A, Dabizzi S, Garaffa G, Fucci R, Falcone P, Bertocci F, Santi R, Criscuoli , Serni S, Carini M, Natali A
- KMID: 2427412
- Clin Exp Reprod Med.
- 2018 Dec;45(4):170-176.
- doi: 10.5653/cerm.2018.45.4.170
OBJECTIVE: To assess whether the “testicular pool†could be used for histological analysis and whether it gave more accurate information than the standard testicular biopsy. METHODS: Between January 2017 and March... -
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- In vitro differentiation of spermatogonial stem cells using testicular cells from Guangxi Bama mini-pig
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Zhao H, Nie J, Zhu X, Lu Y, Liang X, Xu H, Yang X, Zhang Y, Lu K, Lu S
- KMID: 2420927
- J Vet Sci.
- 2018 Sep;19(5):592-599.
- doi: 10.4142/jvs.2018.19.5.592
In this study, we attempted to establish a culture system for in vitro spermatogenesis from spermatogonial stem cells (SSCs) of Bama mini-pig. Dissociated testicular cells from 1-month-old pigs were co-cultured... -
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- Abnormal Human Sperm Parameters Contribute to Sperm DNA Fragmentation in Men with Varicocele
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Park YS, Lee SH, Choi HW, Lee HS, Lee JS, Seo JT
- KMID: 2419324
- World J Mens Health.
- 2018 Sep;36(3):239-247.
- doi: 10.5534/wjmh.180014
PURPOSE: This study was performed to evaluate and compare threshold sperm parameters and sperm DNA fragmentation index (DFI), and further analyzed whether sperm DFI could be predicted from sperm parameters... -
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- Differentiation of human male germ cells from Wharton's jelly-derived mesenchymal stem cells
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Dissanayake D, Patel H, Wijesinghe P
- KMID: 2415102
- Clin Exp Reprod Med.
- 2018 Jun;45(2):75-81.
- doi: 10.5653/cerm.2018.45.2.75
OBJECTIVE: Recapitulation of the spermatogenesis process in vitro is a tool for studying the biology of germ cells, and may lead to promising therapeutic strategies in the future. In this... -
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- Ameliorative effect of vitamin B12 on seminiferous epithelium of cimetidine-treated rats: a histopathological, immunohistochemical and ultrastructural study
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Elsaed WM, Bedeer RF, Eladl MA
- KMID: 2418395
- Anat Cell Biol.
- 2018 Mar;51(1):52-61.
- doi: 10.5115/acb.2018.51.1.52
Cimetidine is an H2 receptor antagonist that has an antiandrogenic effect. It intervenes with the conversion of testosterone into estrogen in the Sertoli cells with accompanying testicular structural changes. In... -
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- An infertile patient with Y chromosome b1/b3 deletion presenting with congenital bilateral absence of the vas deferens with normal spermatogenesis
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Kuroda S, Usui K, Mori K, Yasuda K, Asai T, Sanjo H, Yakanaka H, Takeshima , Kawahara T, Hamanoue H, Kato Y, Miyoshi Y, Uemura H, Iwasaki A, Yumura Y
- KMID: 2408577
- Clin Exp Reprod Med.
- 2018 Mar;45(1):48-51.
- doi: 10.5653/cerm.2018.45.1.48
We report the case of a 46-year-old Chinese male patient who visited our clinic complaining of infertility. Semen analysis revealed azoospermia, and azoospermia factor c region partial deletion (b1/b3) was... -
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- Restoration of Spermatogenesis Using a New Combined Herbal Formula of Epimedium koreanum Nakai and Angelica gigas Nakai in an Luteinizing Hormone-Releasing Hormone Agonist-Induced Rat Model of Male Infertility
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Park HJ, Koo YK, Park MJ, Hwang YK, Hwang SY, Park NC
- KMID: 2398566
- World J Mens Health.
- 2017 Dec;35(3):170-177.
- doi: 10.5534/wjmh.17031
PURPOSE: We investigated the protective effect of a mixture of 2 herbal extracts, KH-465, which consisted of Epimedium koreanum Nakai and Angelica gigas Nakai, on spermatogenesis in a luteinizing hormone-releasing... -
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- Enrichment and In Vitro Culture of Spermatogonial Stem Cells from Pre-Pubertal Monkey Testes
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Kim YH, Kang HG, Kim BJ, Jung SE, Karmakar P, Kim SM, Hwang S, Ryu BY
- KMID: 2394989
- Tissue Eng Regen Med.
- 2017 Oct;14(5):557-566.
- doi: 10.1007/s13770-017-0058-x
Spermatogonial stem cells (SSCs) are essential for spermatogenesis throughout the lifespan of the male. However, the rarity of SSCs has raised the need for an efficient selection method, but little... -
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- Needle Aspiration Biopsy of Seminiferous Tubules (NABST) as a Diagnostic Method in Korea
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Jung JH, Lee TH, Choi KH, Hong JY
- KMID: 2390435
- Chonnam Med J.
- 2017 Sep;53(3):211-215.
- doi: 10.4068/cmj.2017.53.3.211
To evaluate the diagnostic efficacy of needle aspiration biopsy of seminiferous tubules (NABST) and to represent the redistributed diagnostic results corresponding to testicular volumes and follicle-stimulating hormone (FSH) levels. In... -
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- Establishment of a surgically induced cryptorchidism canine recipient model for spermatogonial stem cell transplantation
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Lee WY, Lee R, Song H, Hur TY, Lee S, Ahn J, Jhun H
- KMID: 2362918
- Lab Anim Res.
- 2016 Dec;32(4):257-266.
- doi: 10.5625/lar.2016.32.4.257
Transplantation of spermatogonial stem cells (SSCs) in experimental animal models has been used to study germ line stem cell biology and to produce transgenic animals. The species-specific recipient model preparation... -
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- Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells into the Testes of Infertile Male Rats and New Germ Cell Formation
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Ghasemzadeh-Hasankolaei M, Batavani R, Eslaminejad MB, Sayahpour
- KMID: 2362519
- Int J Stem Cells.
- 2016 Nov;9(2):250-263.
- doi: 10.15283/ijsc16010
BACKGROUND: Mesenchymal stem cells (MSCs), have been suggested as a potential choice for treatment of male infertility. Yet, the effects of MSCs on regeneration of germinal epithelium of seminiferous tubules... -
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- Clinical Outcomes of Varicocele Repair in Infertile Men: A Review
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Chiba K, Fujisawa M
- KMID: 2349846
- World J Mens Health.
- 2016 Aug;34(2):101-109.
- doi: 10.5534/wjmh.2016.34.2.101
Varicoceles are a major cause of impaired spermatogenesis and the most common correctable cause of male infertility. They are found in approximately 40% of men with primary infertility and 80%... -
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- Differential expression of estrogen receptor α and progesterone receptor in the normal and cryptorchid testis of a dog
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Jung HY, Yoo DY, Jo YK, Kim GA, Chung JY, Choi JH, Jang G, Hwang IK
- KMID: 2309087
- Lab Anim Res.
- 2016 Jun;32(2):128-132.
- doi: 10.5625/lar.2016.32.2.128
Descending of the testes is an important process for spermatogenesis and cryptorchidism is one of the most relevant genital defects in dogs. In a previous study, we observed abnormal morphology... -
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- Smoking and Male Infertility: An Evidence-Based Review
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Harlev A, Agarwal A, Gunes SO, Shetty A, du Plessis SS
- KMID: 2405142
- World J Mens Health.
- 2015 Dec;33(3):143-160.
- doi: 10.5534/wjmh.2015.33.3.143
Many studies have reported that the contents of cigarette smoke negatively affect sperm parameters, seminal plasma, and various other fertility factors. Nevertheless, the actual effect of smoking on male fertility... -
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