Clin Pediatr Hematol Oncol.  2016 Apr;23(1):65-69. 10.15264/cpho.2016.23.1.65.

A Case of Malignant Glomus Tumor on Shoulder with Pulmonary Metastasis Treated with Doxorubicin and Ifosfamide in a 10-year Old Girl

• Jin WS
• Jeon IS

• KMID: 2168912
• DOI: http://doi.org/10.15264/cpho.2016.23.1.65

Abstract

Malignant glomus tumor is an exceedingly rare neoplasm occurring in the soft tissues. Controversy exists over whether malignant glomus tumor is a true malignancy due to the rarity of metastasis, however, this neoplasm has been known to show relatively frequent metastasis and poor outcome. To improve the outcome of systemic therapy for malignant glomus tumor might be necessary, but the appropriate chemotherapy or radiotherapy has yet to be elucidated. We report a case of malignant glomus tumor with multiple pulmonary metastases treated with total surgical resection and adjuvant chemotherapy including doxorubicin and ifosfamide; however 7 months after completion of chemotherapy primary lung nodules increased. This case suggests that these chemotherapeutic agents are not effective for the management of malignant glomus tumor with metastasis.

Keyword

Malignant glomus tumor; Chemotherapy

MeSH Terms

Chemotherapy, Adjuvant
Doxorubicin*
Drug Therapy
Female*
Glomus Tumor*
Humans
Ifosfamide*
Lung
Neoplasm Metastasis*
Radiotherapy
Shoulder*
Doxorubicin
Ifosfamide