- Real world effectiveness and safety of pegylated liposomal doxorubicin in platinum-sensitive recurrent ovarian, fallopian, or primary peritoneal cancer: a Korean multicenter retrospective cohort study
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Park SJ, Kim J, Kim HS, Lee JW, Chang HK, Lee KH, Kim DY, Kim S, Chang SJ, Han SS, Park SY, Shim SH
- KMID: 2470868
- J Gynecol Oncol.
- 2020 Mar;31(2):e15.
- doi: 10.3802/jgo.2020.31.e15
OBJECTIVE: To evaluate the effectiveness and safety of the combination of pegylated liposomal doxorubicin with carboplatin (CD) compared with those of carboplatin and paclitaxel (CP) for platinum-sensitive recurrent ovarian, fallopian,... -
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- Olaratumab and doxorubicin for the treatment of metastatic soft tissue sarcoma: a retrospective case series
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Hur JY, Park SH, Lee SJ
- KMID: 2469530
- Precis Future Med.
- 2019 Jun;3(2):77-84.
- doi: 10.23838/pfm.2019.00016
PURPOSE: Soft tissue sarcomas (STS) are a rare and heterogeneous tumor group with limited treatment options. This study aimed to evaluate the anti-tumor efficacy of olaratumab and doxorubicin in patients... -
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- Doxorubicin Promotes Migration and Invasion of Breast Cancer Cells through the Upregulation of the RhoA/MLC Pathway
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Liu CL, Chen MJ, Lin JC, Lin CH, Huang WC, Cheng SP, Chen SN, Chang YC
- KMID: 2450114
- J Breast Cancer.
- 2019 Jun;22(2):185-195.
- doi: 10.4048/jbc.2019.22.e22
PURPOSE: Cancer cells develop acquired resistance induced by chemotherapeutic drugs. In this study, we investigated the effects of brief treatment with cytotoxic drugs on the phenotype of breast cancer cells. METHODS:... -
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- Loss of endogenous estrogen increases cardiac toxicity by doxorubicin
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Lee YH, Lee SR, Kwon SW, Lee SY, Park BK, Hong EJ
- KMID: 2405359
- J Biomed Transl Res.
- 2017 Dec;18(4):146-150.
- doi: 10.12729/jbtr.2017.18.4.146
Breast cancer is of enormous concern worldwide and linked with age, sex, hormonal factors, and family history. The treatment of early breast cancer includes treating the disease locally with surgery,... -
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- The efficacy and safety of pegylated liposomal doxorubicin monotherapy and combination therapy with carboplatin in Korean patients with recurrent ovarian, fallopian tube, or primary peritoneal cancer: a single-institution experience
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Lee YJ, Kim YM, Lee SW, Park JY, Kim DY, Suh DS, Kim JH, Kim YT, Nam JH
- KMID: 2393842
- Obstet Gynecol Sci.
- 2017 Sep;60(5):433-439.
- doi: 10.5468/ogs.2017.60.5.433
OBJECTIVE: This study aimed to evaluate the efficacy and safety of pegylated liposomal doxorubicin (PLD) with or without carboplatin in Korean patients with recurrent ovarian cancer (ROC), fallopian tube, or... -
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- Non-homologous End Joining Inhibitor SCR-7 to Exacerbate Low-dose Doxorubicin Cytotoxicity in HeLa Cells
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Kumar A, Bhatkar D, Jahagirdar D, Sharma NK
- KMID: 2375548
- J Cancer Prev.
- 2017 Mar;22(1):47-54.
- doi: 10.15430/JCP.2017.22.1.47
Among the genotoxic drug regimens, doxorubicin (DOX) is known for its high-dose side effects in several carcinomas, including cervical cancer. This study reports on testing the combined use of a... -
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- Human Herpesvirus 8–Unrelated Primary Effusion Lymphoma–Like Lymphoma in an Elderly Korean Patient with a Good Response to Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone
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Shin J, Lee JO, Choe JY, Bang SM, Lee JS
- KMID: 2367525
- Cancer Res Treat.
- 2017 Jan;49(1):274-278.
- doi: 10.4143/crt.2016.076
Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin’s lymphoma arising from a B-cell lineage characterized by the formation of malignant effusion in body cavities without evidence of a... -
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- Survival Outcome of Combined GnRH Agonist and Tamoxifen Is Comparable to That of Sequential Adriamycin and Cyclophosphamide Chemotherapy Plus Tamoxifen in Premenopausal Patients with Lymph-Node–Negative, Hormone-Responsive, HER2-Negative, T1-T2 Breast Cancer
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Sohn G, Ahn SH, Kim HJ, Son BH, Lee JW, Ko BS, Lee Y, Lee SB, Baek S
- KMID: 2356237
- Cancer Res Treat.
- 2016 Oct;48(4):1351-1362.
- doi: 10.4143/crt.2015.444
PURPOSE: The purpose of this study was to compare treatment outcomes between combined gonadotropin-releasing hormone agonist and tamoxifen (GnRHa+T) and sequential adriamycin and cyclophosphamide chemotherapy and tamoxifen (AC->T) in premenopausal... -
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- Involvement of NRF2 Signaling in Doxorubicin Resistance of Cancer Stem Cell-Enriched Colonospheres
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Ryoo IG, Kim G, Choi BH, Lee SH, Kwak MK
- KMID: 2351671
- Biomol Ther.
- 2016 Sep;24(5):482-488.
- doi: 10.4062/biomolther.2016.145
Cancer stem cells (CSCs) are a subset of tumor cells, which are characterized by resistance against chemotherapy and environmental stress, and are known to cause tumor relapse after therapy. A... -
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- Metronomic capecitabine versus doxorubicin in advanced hepatocellular carcinoma
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Khedr GA, Elzawawy S, Gowil AG, Elyamany A, Eshafei M
- KMID: 2360701
- Korean J Clin Oncol.
- 2016 Jun;12(1):32-40.
- doi: 10.14216/kjco.16006
PURPOSE: We evaluated oral metronomic capecitabine (MC) compared to intravenous doxorubicin in patients with advanced or metastatic hepatocellular carcinoma (HCC). METHODS: From January 2013 to December 2015, patients with Child-Pugh class... -
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- A Case of Malignant Glomus Tumor on Shoulder with Pulmonary Metastasis Treated with Doxorubicin and Ifosfamide in a 10-year Old Girl
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Jin WS, Jeon IS
- KMID: 2168912
- Clin Pediatr Hematol Oncol.
- 2016 Apr;23(1):65-69.
- doi: 10.15264/cpho.2016.23.1.65
Malignant glomus tumor is an exceedingly rare neoplasm occurring in the soft tissues. Controversy exists over whether malignant glomus tumor is a true malignancy due to the rarity of metastasis,... -
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- Reduced Dose Intensities of Doxorubicin in Elderly Patients with DLBCL in Rituximab Era
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Ha H, Keam B, Kim TM, Jeon YK, Lee SH, Kim DW, Kim CW, Heo DS
- KMID: 2152289
- Cancer Res Treat.
- 2016 Jan;48(1):304-311.
- doi: 10.4143/crt.2014.339
PURPOSE: The dose intensity of doxorubicin (DID) is important to the survival of diffuse large B cell lymphoma (DLBCL) patients. However, due to expected toxicities, most elderly patients cannot receive... -
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- The Alginate Layer for Improving Doxorubicin Release and Radiolabeling Stability of Chitosan Hydrogels
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Kwon JI, Lee CM, Jeong HS, Oh PS, Hwang H, Lim ST, Sohn MH, Jeong HJ
- KMID: 2132237
- Nucl Med Mol Imaging.
- 2015 Dec;49(4):312-317.
- doi: 10.1007/s13139-015-0337-1
PURPOSE: Chitosan hydrogels (CSH) formed through ionic interaction with an anionic molecule are suitable as a drug carrier and a tissue engineering scaffold. However, the initial burst release of drugs... -
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- A Randomized Phase II Trial of Capecitabine Plus Vinorelbine Followed by Docetaxel Versus Adriamycin Plus Cyclophosphamide Followed by Docetaxel as Neoadjuvant Chemotherapy for Breast Cancer
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Yoo C, Kim SB, Ahn JH, Kim JE, Jung KH, Gong GY, Son BH, Ahn SH, Ahn SD, Kim HH, Shin HJ, Kim WK
- KMID: 2148489
- Cancer Res Treat.
- 2015 Jul;47(3):406-415.
- doi: 10.4143/crt.2014.073
PURPOSE: Given the promising activity of capecitabine and vinorelbine in metastatic breast cancer, this randomized phase II trial evaluated the efficacy and safety of this combination as neoadjuvant chemotherapy in... -
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- Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy for diffuse large B-cell lymphoma in pregnancy may be associated with preterm birth
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Lee EJ, Ahn KH, Hong SC, Lee EH, Park Y, Kim BS
- KMID: 2314021
- Obstet Gynecol Sci.
- 2014 Nov;57(6):526-529.
- doi: 10.5468/ogs.2014.57.6.526
Lymphoma, especially non-Hodgkin's lymphoma is extremely rare in pregnancy. A 24-year-old pregnant woman was diagnosed with diffuse large B-cell lymphoma (DLBCL), a subgroup of non-Hodgkin's lymphoma, at 24 weeks' gestation,... -
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- Effects of adriamycin and candesartan on the collagen and elastin of the aorta in rats
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Uhm JS, Chung WB, Yoon JS, Oh YS, Youn HJ
- KMID: 2380252
- Clin Hypertens.
- 2014 ;20(3):8.
- doi: 10.1186/2056-5909-20-8
INTRODUCTION: It has been reported that the chemotherapeutic agent, adriamycin, not only has an effect on the myocardium but also on the arteries. The aim of this study is to... -
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- Primary diffuse large B-cell lymphoma of the bone marrow in a frail and elderly patient successfully treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone
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Niscola P, Palombi M, Fratoni S, Perrotti A, de Fabritiis P
- KMID: 2172880
- Blood Res.
- 2013 Dec;48(4):296-297.
- doi: 10.5045/br.2013.48.4.296
No abstract available. -
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- Histological Experimental Study on the Effect of Stem Cell Therapy on Adriamycin Induced Chemobrain
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Zickri1 MB, Abd El Aziz DH, Metwally H
- KMID: 2054550
- Int J Stem Cells.
- 2013 Nov;6(2):104-112.
BACKGROUND AND OBJECTIVES: Negative consequences of chemotherapy on brain function were suggested and were addressed in animal models as the clinical phenomenon of chemobrain .It was postulated that adriamycin (ADR)... -
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- Interrelation between Expression of ADAM 10 and MMP 9 and Synthesis of Peroxynitrite in Doxorubicin Induced Cardiomyopathy
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Lim SC
- KMID: 2048308
- Biomol Ther.
- 2013 Sep;21(5):371-380.
Doxorubicin is still main drug in chemotherapy with limitation of use due to adverse drug reaction. Increased oxidative stress and alteration of nitric oxide control have been involved in cardiotoxicity... -
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- Increases in Doxorubicin Sensitivity and Radioiodide Uptake by Transfecting shMDR and Sodium/Iodide Symporter Gene in Cancer Cells Expressing Multidrug Resistance
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Ahn SJ, Lee YJ, Lee YL, Choi CI, Lee SW, Yoo J, Ahn BC, Lee IK, Lee J
- KMID: 1518943
- Nucl Med Mol Imaging.
- 2007 Jun;41(3):209-217.
PURPOSE: Multidrug resistance (MDR) of the cancer cells related to mdr1 gene expression can be effectively treated by selective short hairpin RNA for mdr1 gene (shMDR). Sodium/iodide symporter (NIS) gene... -
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