Korean J Urol.  1984 Apr;25(2):149-153.

Therapy and Prophylaxis for superficial Bladder Tumors: Doxorubicin and Thio-tepa

• Park WS
• Lee SC

Abstract

20 cases of study group whose follow-up period is over 6 months among 22 cases of bladder tumors treated with doxorubicin instillation following TUR during the period from December, 1981 through December, 1983 were compared with 30 cases of controlled group whose follow-up period is over 6 months among 32 cases of bladder tumors treated with thio-tepa instillation following TUR during the period from January, 1978 through June, 1981. Following result were obtained. 1. Recurrence rate In TUR + doxorubicin, 25%, In TUR+thio-tepa,30% 2. Interval between TUR & the first recurrence: In TUR + doxorubicin, average 9 months, In TUR + thio-tepa, average 8.1 months 3. Complication: In TUR + doxorubicin, painful urination in 2 cases(10%), In TUR + thio-tepa, hematuria, dysuria, painful urination, and urethral stricture in 8 cases(26.7%).

Keyword

superficial bladder tumor; doxorubicin; thiotepa

MeSH Terms

Doxorubicin*
Dysuria
Follow-Up Studies
Hematuria
Recurrence
Thiotepa*
Urethral Stricture
Urinary Bladder Neoplasms*
Urinary Bladder*
Urination
Doxorubicin
Thiotepa