Allergy Asthma Respir Dis.  2015 May;3(3):219-223. 10.4168/aard.2015.3.3.219.

Mixed plant extract-dependent exercise-induced anaphylaxis

Affiliations
  • 1Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jhlovechild@gmail.com
  • 2Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, Korea.

Abstract

Food-dependent exercise-induced anaphylaxis (FDEIA) is a potentially life-threatening clinical reaction in which anaphylaxis develops when physical activity occurs within a few hours after ingesting a specific food. An 18-year-old girl experienced generalized urticaria, periorbital swelling, and dyspnea repeatedly by exercise after intake of a red ginseng health supplement. A confirmed diagnosis was established in this case by using an exercise challenge test after ingesting mixed-plant extract containing red ginseng health supplement. To the best of our knowledge, this is the first case of FDEIA caused by components in a red ginseng health supplement.

Keyword

Panax ginseng; Exercise; Anaphylaxis

MeSH Terms

Adolescent
Anaphylaxis*
Diagnosis
Dyspnea
Female
Humans
Motor Activity
Panax
Plants*
Urticaria

Figure

  • Fig. 1 Specific IgE was not detected in the patient and normal control by enzyme-linked immunosorbent assay.

  • Fig. 2 Different sized protein bands were shown in fresh ginseng by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. On the other hand, protein bands were not identified in red ginseng powder and health product. M, marker: 1, fresh ginseng powder; 2, red ginseng powder: 3, red ginseng product.


Cited by  1 articles

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Allergy Asthma Respir Dis. 2018;6(Suppl 1):S21-S30.    doi: 10.4168/aard.2018.6.S1.S21.


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