Ann Surg Treat Res.  2014 Jun;86(6):289-294. 10.4174/astr.2014.86.6.289.

Higher incidence of gastroesophageal reflux disease after gastric wedge resections of gastric submucosal tumors located close to the gastroesophageal junction

• Ko SY
• Lee JS
• Kim JJ
• Park SM

• KMID: 2167105
• DOI: http://doi.org/10.4174/astr.2014.86.6.289

Abstract

PURPOSE
We hypothesized that gastroesophageal reflux disease (GERD) would be more prevalent after a gastric wedge resection of a submucosal tumor (SMT) located close to the gastroesophageal junction (GEJ) than after a gastric wedge resection of an SMT at other locations because of the damage to the lower esophageal sphincter during surgery.
METHODS
Fifty-eight patients with gastric SMT who underwent open or laparoscopic gastric wedge resection between January 2000 and August 2012 at the Department of Surgery, Incheon St. Mary's Hospital were enrolled into this study. The patients were divided into 2 groups according to the location of the tumor, upper or lateral border of the tumor within 5 cm of the GEJ (GEJ < or = 5 cm group) and upper or lateral border of the tumor greater than 5 cm distal to the GEJ (GEJ > 5 cm group). The surgical records, clinicopathologic findings, postoperative GERD symptoms, postoperative use of acid suppressive medications and preoperative and postoperative endoscopic findings were retrospectively reviewed and compared between the 2 groups.
RESULTS
There was no difference in the frequency of the preoperative GERD symptoms between the 2 groups, whereas postoperative GERD symptoms and postoperative use of acid suppressive medications were more frequent in the GEJ < or = 5 cm group (P = 0.045 and P = 0.031). However, there were no differences in the follow-up endoscopic findings in terms of reflux esophagitis and Hill's grade between the 2 groups.
CONCLUSION
The incidence of GERD was higher after gastric wedge resection of SMTs located close to the GEJ. Hence, adequate care should be taken during the follow-up of these patients.

Keyword

Gastric wedge resection; Esophagogastric Junction; Gastroesophageal reflux

MeSH Terms

Esophageal Sphincter, Lower
Esophagitis, Peptic
Esophagogastric Junction*
Follow-Up Studies
Gastroesophageal Reflux*
Humans
Incheon
Incidence*
Retrospective Studies

Figure

• 

  Fig. 1 Illustration for the hypothesis of the development of gastroesophageal reflux disease after a gastric wedge resection for a submucosal tumor located close to the gastroesophageal junction. If the upper or lateral border of the tumor is located within 5 cm from the gastroesophageal junction, there is a substantial risk of damage to the lower esophageal sphincter, especially to the sling fibers after wedge resection for this tumor.

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