Cancer Res Treat.
2007 Jun;39(2):88-91.
A Case of Organizing Pneumonia Associated with Rituximab
- Affiliations
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- 1Department of 1Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea. sykim@khu.ac.kr
- 2Department of Pathology, Kyung Hee University College of Medicine, Seoul, Korea.
Abstract
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Rituximab is a human/murine chimeric anti-CD20 mono- clonal antibody used to treat CD20-positive B-cell non- Hodgkin's lymphoma (NHL). Although most of the adverse effects associated with rituximab are usually reversible and temporary infusion-related reactions, including fever, chills, flushing and skin reactions, there are several reports of pulmonary events after long-term administration of rituximab. We present a case of asymp-tomatic nodular organizing pneumonia occurring during rituximab-based chemotherapy in a patient with non- Hodgkin's lymphoma.