Cancer Res Treat.  2007 Jun;39(2):88-91.

A Case of Organizing Pneumonia Associated with Rituximab

Affiliations
  • 1Department of 1Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea. sykim@khu.ac.kr
  • 2Department of Pathology, Kyung Hee University College of Medicine, Seoul, Korea.

Abstract

Rituximab is a human/murine chimeric anti-CD20 mono- clonal antibody used to treat CD20-positive B-cell non- Hodgkin's lymphoma (NHL). Although most of the adverse effects associated with rituximab are usually reversible and temporary infusion-related reactions, including fever, chills, flushing and skin reactions, there are several reports of pulmonary events after long-term administration of rituximab. We present a case of asymp-tomatic nodular organizing pneumonia occurring during rituximab-based chemotherapy in a patient with non- Hodgkin's lymphoma.

Keyword

Rituximab; Organizing pneumonia; Non-Hodgkin's lymphoma

MeSH Terms

B-Lymphocytes
Chills
Drug Therapy
Fever
Flushing
Hodgkin Disease
Humans
Lymphoma, Non-Hodgkin
Pneumonia*
Skin
Rituximab
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