J Korean Soc Radiol.  2016 May;74(5):308-312. 10.3348/jksr.2016.74.5.308.

Rapid Progression of Mediastinal Tumor within a Few Days: A Case Report of T Cell Lymphoblastic Lymphoma

Affiliations
  • 1Department of Radiology, Seoul Medical Center, Seoul, Korea. ykradio@medimail.co.kr
  • 2Department of Hematooncology, Seoul Medical Center, Seoul, Korea.
  • 3Department of Pathology, Seoul Medical Center, Seoul, Korea.
  • 4Department of Thoracic Surgery, Seoul Medical Center, Seoul, Korea.

Abstract

T-cell lymphoblastic lymphoma is a highly aggressive tumor derived from lymphocyte of the thymus, which accounts for 2% of non-Hodgkin's lymphoma. The disease occurs most commonly in adolescent and young adult males. It often results in respiratory emergency because of high proliferation rate. In this case, we confirmed the rapid progression of T-cell lymphoblastic lymphoma through the chest CT scan with one week interval. Three days of empirical chemotherapy resulted in substantial reduction of mediastinal mass, pleural thickening and pleural effusion.


MeSH Terms

Adolescent
Drug Therapy
Emergencies
Humans
Lymphocytes
Lymphoma, Non-Hodgkin
Male
Mediastinal Neoplasms
Pleural Effusion
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
T-Lymphocytes
Thymus Gland
Tomography, X-Ray Computed
Young Adult

Reference

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2. Hoelzer D, Gökbuget N. T-cell lymphoblastic lymphoma and T-cell acute lymphoblastic leukemia: a separate entity? Clin Lymphoma Myeloma. 2009; 9:Suppl 3. S214–S221.
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