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Effect of melatonin on the onset of puberty in male juvenile rats

Venugopal

Melatonin or N-acetyl-5-methoxytryptamine, the fascinating molecule secreted by the pineal gland. Melatonin has a close interaction with hypothalamic-pituitary-gonadal axis. In non-seasonal breeders like rat its exact role in reproduction is...
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Effect of Yeonsan Ogye bioactive peptides on anti-oxidant indexes in rats' liver

Kim HW, Shim JH, Kim KN

PURPOSE: This study investigated the effect of bioactive Yeonsan Ogye peptides (YOPs) intake on changes in the hepatic anti-oxidant indexes in male rats. METHODS: Sprague-Dawley male rats were divided into 3...
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Primary Extraskeletal Osteosarcoma in the Anterior Mediastinum: A Case Report and Review

Joo S, Song JW, Na KJ, Park S, Park IK, Kim YT, Kang CH

Extraskeletal osteosarcoma (ESOS) is a malignant soft tissue neoplasm producing osteoid, without any continuity with the bone or periosteum. Primary ESOS presenting in the mediastinum is an extremely rare, yet...
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CD24⁺ Cell Depletion Permits Effective Enrichment of Thymic iNKT Cells While Preserving Their Subset Composition

Park JY, Kwon J, Kim EY, Fink J, Kim HK, Park JH

Invariant NKT (iNKT) cells are a small subset of thymus-generated T cells that produce cytokines to control both innate and adaptive immunity. Because of their very low frequency in the...
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A large thymic mass with persistent active tissue in an elderly cadaver

Tripathy P, Chaudhary , Gaikwad MR, Britto NJ

Thymus is an encapsulated organ having its bilateral origin from the third pharyngeal pouch. It appears to be a single organ but actually it is bilobed. It attains its maximum...
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Global Variations in Curriculum and Syllabus for Endocrine Surgery Training Programs: a Report

Yadav SK, Mishra SK

PURPOSE: The aim of this study is to find out information relevant to the certification of trainees in surgical endocrinology specialty—duration of training, entry/exit criteria, curriculum and accreditation agency. METHODS: Information...
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Screening of the growth of thymus of human fetuses

Asghar A, Asad MR, Naaz S, Rani M

The thymus is a lymphoepithelial organ, and its morphometry is commonly utilized for surveillance of the immunological status of fetus and neonates. Many studies showed that fetal thymus size is...
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Clinical significance of T cell receptor excision circle (TREC) quantitation after allogenic HSCT

Mikhael NL, Elsorady M

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a well-established treatment modality for a variety of diseases. Immune reconstitution is an important event that determines outcomes. The immune recovery of T...
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A Case of Large Cell Neuroendocrine Carcinoma of the Maxillary Sinus

Lee YJ, Jeong JH, Oh YH, Ji YB

Large cell neuroendocrine carcinoma is a rare epithelial neuroendocrine malignancy and is preferentially located in gastrointestinal tract and pancreas. Cases of large cell neuroendocrine carcinoma have been reported in many...
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CD57 (Leu-7, HNK-1) immunoreactivity seen in thin arteries in the human fetal lung

Ishizuka S, Jin ZW, Yamamoto M, Murakami G, Takayama T, Hayashi K, Abe SI

CD57 (synonyms: Leu-7, HNK-1) is a well-known marker of nerve elements including the conductive system of the heart, as well as natural killer cells. In lung specimens from 12 human...
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Higher incidence of sperm granuloma in the epididymis of C57BL/6N mice

Park DY, Lee BS, Kim WJ, Im WJ, Han JS, Park H, Yang MJ, Cho JW, Kim DH, Han SC, Kim YB, Son HY

C57BL/6N mice are inbred strains widely used in biomedical research. Hence, a large amount of basic data has been accumulated. However, in the field of histopathology, spontaneous data for relatively...
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Optimization of Algerian Thymus fontanesii Boiss. & Reut Essential Oil Extraction by Electromagnetic Induction Heating

Sid Ali L, Brada M, Fauconnier ML, Kenne T

The present study deals with the determination of optimal values of operating parameters such as the temperature of heating, the mass of the plant material and the volume of water...
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CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice

Kim JI, Park JS, Kwak J, Lim HJ, Ryu SK, Kwon E, Han KM, Nam KT, Lee HW, Kang BC

CD47 (integrin-associated protein), a multi-spanning transmembrane protein expressed in all cells including red blood cells (RBCs) and leukocytes, interacts with signal regulatory protein α (SIRPα) on macrophages and thereby inhibits...
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CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice

Kim JI, Park JS, Kim H, Ryu SK, Kwak J, Kwon E, Yun JW, Nam KT, Lee HW, Kang BC

Recombination activating gene-2 (RAG-2) plays a crucial role in the development of lymphocytes by mediating recombination of T cell receptors and immunoglobulins, and loss of RAG-2 causes severe combined immunodeficiency...
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Cytologic Characteristics of Thymic Adenocarcinoma with Enteric Differentiation: A Study of Four Fine-Needle Aspiration Specimens

Kwon AY, Han J, Cho HY, Kim S, Bang H, Hyeon J

Thymic adenocarcinoma is extremely rare. Although its histologic features have been occasionally reported, a lack of description of the cytologic features has hampered the prompt and accurate diagnosis of this...
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Ectopic Cervical Thymoma: A Case Report and Review

Park HO, Kim SH, Moon SH, Yang JH, Kang DH, Lee JH

In the embryo, the thymus originates from the third and fourth pharyngeal pouches and migrates from the superior neck to the mediastinum. Ectopic cervical thymoma (ECT) is an extremely rare...
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Comparison of humoral and cell-mediated immunity in three different C57BL/6N mouse substrains

Kim HR, Choi JY, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK

Adaptive immunity is a type of immune response mediated by T and B cells, and is important response for immune response amplification and memory. In this study, the adaptive immunologic...
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Comparative study of the immunological characteristics of three different C57BL/6N mouse substrains

Choi JY, Kim HR, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK

Inbred mice, a systematically developed homogeneous animal, have been developed to maintain experimental reproducibility and to minimize experimental variables in animal-based studies. In particular, C57BL/6 mice are frequently used in...
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Multiple Thymoma with Myasthenia Gravis

Seo DH, Cho S

The actual incidence of multiple thymoma is unknown and rarely reported because it remains controversial whether the cases represent a disease of multicentric origin or a disease resulting from intrathymic...
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Epidural Metastasis in Malignant Thymoma Mimicking Epidural Abscess: Case Report and Literature Review

Kim JY, Lee YS, Kang DH, Kim MH, Lee JH, Lee CH, Park IS

Thymoma and thymic carcinoma are rare epithelial tumors that originate from the thymus gland. Extrathoracic metastases occur in the liver, kidney, and bone in 1% to 15% of patients. Although...
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