Korean J Blood Transfus.  2016 Apr;27(1):1-11. 10.17945/kjbt.2016.27.1.1.

Pathogen Reduction for Platelets

• Kwon SY

• KMID: 2163115
• DOI: http://doi.org/10.17945/kjbt.2016.27.1.1

Abstract

Although application of multiple safety measures like donor screening and screening for infectious agents has made blood transfusion safer than ever, blood safety remains a hot topic in transfusion medicine. Emerging pathogens constantly threaten the safety of blood and current safety measures have their limitations in addressing these matters. Pathogen reduction technologies have been developed as a proactive approach to overcoming these limitations. This paper outlines the efficacy of pathogen reduction technologies that are currently applied for platelets for clinical use. Their clinical efficacy and safety issues and other effects are also reviewed.

Keyword

Pathogen reduction technology; Platelets; Emerging pathogens

MeSH Terms

Blood Safety
Blood Transfusion
Donor Selection
Mass Screening
Transfusion Medicine