Korean Circ J.  2012 Aug;42(8):519-520. 10.4070/kcj.2012.42.8.519.

Possible Regulation of Platelets by Native and Modified Low Density Lipoprotein-Cholesterol Particles

• Han KH

• KMID: 2225000
• DOI: http://doi.org/10.4070/kcj.2012.42.8.519

Abstract

No abstract available.

MeSH Terms

Blood Platelets

Reference

1. Grundtman C, Wick G. The autoimmune concept of atherosclerosis. Curr Opin Lipidol. 2011. 22:327–334.

2. Siess W. Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein. Pathophysiol Haemost Thromb. 2006. 35:292–304.

3. Siegel-Axel D, Daub K, Seizer P, Lindemann S, Gawaz M. Platelet lipoprotein interplay: trigger of foam cell formation and driver of atherosclerosis. Cardiovasc Res. 2008. 78:8–17.

4. Zimman A, Podrez EA. Regulation of platelet function by class B scavenger receptors in hyperlipidemia. Arterioscler Thromb Vasc Biol. 2010. 30:2350–2356.

5. Akkerman JW. From low-density lipoprotein to platelet activation. Int J Biochem Cell Biol. 2008. 40:2374–2378.

6. Hackeng CM, Huigsloot M, Pladet MW, Nieuwenhuis HK, van Rijn HJ, Akkerman JW. Low-density lipoprotein enhances platelet secretion via integrin-alphaIIbbeta3-mediated signaling. Arterioscler Thromb Vasc Biol. 1999. 19:239–247.

7. Kang DY, Park KW, Lee SR, et al. Lack of association between low density lipoprotein particle size and on-treatment platelet reactivity in patients with coronary artery disease. Korean Circ J. 2012. 42:551–557.

8. Pontrelli L, Parris W, Adeli K, Cheung RC. Atorvastatin treatment beneficially alters the lipoprotein profile and increases low-density lipoprotein particle diameter in patients with combined dyslipidemia and impaired fasting glucose/type 2 diabetes. Metabolism. 2002. 51:334–342.

9. Maschberger P, Bauer M, Baumann-Siemons J, et al. Mildly oxidized low density lipoprotein rapidly stimulates via activation of the lysophosphatidic acid receptor Src family and Syk tyrosine kinases and Ca2+ influx in human platelets. J Biol Chem. 2000. 275:19159–19166.