J Korean Orthop Res Soc.  2015 Dec;18(2):74-83. 10.0000/jkors.2015.18.2.74.

Animal Models for Tendon and Ligament

• Park CY
• Jo CH

• KMID: 2162813
• DOI: http://doi.org/10.0000/jkors.2015.18.2.74

Abstract

Tendon and ligament disorders are common and lead to significant disability, pain, healthcare cost, and lost productivity. To study the pathogenesis and management strategies of tendon and ligament injury, appropriate choice and analysis of research models is essential. A number of animal models for tendon and ligament injuries are designed to mimic distinct clinical diseases to better evaluate underlying mechanisms and potential treatments. In this review, we discuss the common methods used for inducing animal models related to tendon and ligament injury as well as the variables for assessing outcome that may be used in animal researchs.

Keyword

Tendon; Ligament; Animal model; Animal research; Translational research

MeSH Terms

Animal Experimentation
Animals*
Efficiency
Health Care Costs
Ligaments*
Models, Animal*
Tendons*
Translational Medical Research