Korean J Otorhinolaryngol-Head Neck Surg.  2016 Apr;59(4):313-316. 10.3342/kjorl-hns.2016.59.4.313.

Epstein-Barr Virus Positive Primary Lymphoepithelial Carcinoma of the Parotid Gland with Hot Uptake of the Nasopharynx at Positron Emission Tomography-Computed Tomography

Affiliations
  • 1Department of Otorhinolaryngology, College of Medicine, Gyeongsang National University, Jinju, Korea. lesaby@hanmail.net
  • 2Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju, Korea.

Abstract

Lymphoepithelial carcinoma (LEC) is a rare histological type of cancer of the salivary glands. LEC is characterized histologically as non-keratinizing, undifferentiated squamous cell carcinoma with lymphocytic infiltration. According to several in-situ hybridization studies, LEC is strongly associated with Epstein-Barr virus (EBV) infection. We report, along with a review of literature, a rare case of EBV positive primary LEC of the parotid that excluded the possibility of coexisting or metastatic nasopharyngeal carcinoma.

Keyword

Epstein-Barr virus; Lymphoepithelial carcinoma; Parotid gland

MeSH Terms

Carcinoma, Squamous Cell
Electrons*
Herpesvirus 4, Human*
Nasopharynx*
Parotid Gland*
Salivary Gland Neoplasms
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