Korean J Otorhinolaryngol-Head Neck Surg.  2009 Jul;52(7):604-607. 10.3342/kjorl-hns.2009.52.7.604.

Lymphoepitherial Carcinoma of the Parotid Gland ; Clinical Report of Three Cases

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea. mdbsk@paran.com

Abstract

Lymphoepithelial carcinoma is a rare but unique malignancy of the major salivary glands. The incidence of lymphoepithelial carcinoma is 0.4-1.4% of the major salivary malignant neoplasms. According to several serologic, immunohistochemical, and in situ hybridization studies, lymphoepithelial carcinoma is strongly associated with Ebstein-Barr virus infection. We present three cases of lymphoepithelial carcinoma associated Ebstein-Barr virus in the parotid gland, which was first presented with a painless and gradually enlarging infraauricular mass. We reoport on the clinical investigation, cytologic, histopathologic features and proper management. Along with a review of literature.

Keyword

Parotid gland; Lymphoepithelial carcinoma

MeSH Terms

In Situ Hybridization
Incidence
Parotid Gland
Salivary Glands
Viruses
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