J Korean Med Assoc.  2016 Apr;59(4):256-265. 10.5124/jkma.2016.59.4.256.

Management of long-term gastric cancer survivors in Korea

Affiliations
  • 1Department of Family Medicine/Cancer Survivorship Clinic, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Family Medicine/Cancer Prevention Clinic, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sws@amc.seoul.kr
  • 3Division of Stomach Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

The incidence of gastric cancer is high, and gastric cancer has one of the highest survival rates of any type of cancer in Korea. With increased long-term survival in a growing number of patients, more patients suffer from health problems such as treatment-related symptoms, malnutrition, chronic diseases, anxiety, and depression. Gastric cancer survivors also have a higher risk of developing a second primary cancer and recurrence. Therefore, survivorship care guidelines for gastric cancer survivors that address surveillance for recurrence, screening for second primary cancers, assessment and management of physical and psychosocial long-term effects of cancer and its treatment, health promotion, and care coordination are needed. The role of primary care physicians is essential for providing continuous care to gastric cancer survivors and their family.

Keyword

Stomach neoplasms; Survivors; Neoplasms, second primary; Physicians, primary care

MeSH Terms

Anxiety
Chronic Disease
Depression
Health Promotion
Humans
Incidence
Korea*
Malnutrition
Mass Screening
Neoplasms, Second Primary
Physicians, Primary Care
Recurrence
Stomach Neoplasms*
Survival Rate
Survivors*

Reference

1. Korea Central Cancer Registry. Annual report of cancer statistics in Korea in 2013. Goyang: Korea Central Cancer Registry;2015.
2. Choi IJ. Gastric cancer screening and diagnosis. Korean J Gastroenterol. 2009; 54:67–76.
Article
3. Ryu KW. Recent advances in minimally invasive surgery for gastric cancer. J Korean Med Assoc. 2015; 58:197–200.
Article
4. Park SR, Kang YK. Perioperative treatments for resectable gastric cancer. J Korean Med Assoc. 2015; 58:201–208.
Article
5. Kong SH, Yang HK. Postoperative follow-up of early gastric cancer. J Korean Med Assoc. 2010; 53:324–330.
Article
6. Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, Aprile G, Kulikov E, Hill J, Lehle M, Ruschoff J, Kang YK. ToGA Trial Investigators. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomized controlled trial. Lancet. 2010; 376:687–697.
Article
7. Min BH, Kim KM. Recent advances in endoscopic diagnosis and treatment of gastric cancer. J Korean Med Assoc. 2015; 58:191–196.
Article
8. Lee HJ, Kim YH, Kim WH, Lee KU, Choe KJ, Kim JP, Yang HK. Clinicopathological analysis for recurrence of early gastric cancer. Jpn J Clin Oncol. 2003; 33:209–214.
Article
9. Sano T, Sasako M, Kinoshita T, Maruyama K. Recurrence of early gastric cancer: follow-up of 1475 patients and review of the Japanese literature. Cancer. 1993; 72:3174–3178.
Article
10. Kodera Y, Ito S, Yamamura Y, Mochizuki Y, Fujiwara M, Hibi K, Ito K, Akiyama S, Nakao A. Follow-up surveillance for recurrence after curative gastric cancer surgery lacks survival benefit. Ann Surg Oncol. 2003; 10:898–902.
Article
11. Yang HK. Information Committee of the Korean Gastric Cancer Association. Current status of clinical practice for gastric cancer patients in Korea: a nationwide survey. J Korean Gastric Cancer Assoc. 2004; 4:95–108.
Article
12. Kim JJ, Lee JH, Jung HY, Lee GH, Cho JY, Ryu CB, Chun HJ, Park JJ, Lee WS, Kim HS, Chung MG, Moon JS, Choi SR, Song GA, Jeong HY, Jee SR, Seol SY, Yoon YB. EMR for early gastric cancer in Korea: a multicenter retrospective study. Gastrointest Endosc. 2007; 66:693–700.
13. Chung IK, Lee JH, Lee SH, Kim SJ, Cho JY, Cho WY, Hwangbo Y, Keum BR, Park JJ, Chun HJ, Kim HJ, Kim JJ, Ji SR, Seol SY. Therapeutic outcomes in 1000 cases of endoscopic submucosal dissection for early gastric neoplasms: Korean ESD Study Group multicenter study. Gastrointest Endosc. 2009; 69:1228–1235.
Article
14. Hosokawa O, Kaizaki Y, Watanabe K, Hattori M, Douden K, Hayashi H, Maeda S. Endoscopic surveillance for gastric remnant cancer after early cancer surgery. Endoscopy. 2002; 34:469–473.
Article
15. Jang HJ, Choi MH, Shin WG, Kim KH, Baek IH, Kim KO, Park CH, Kim JB, Baik KH, Kae SH, Kim HY. Is annual endoscopic surveillance necessary for the early detection of gastric remnant cancer in Korea? A retrospective multi-center study. Hepatogastroenterology. 2014; 61:1283–1286.
16. Kim SG, Jung HK, Lee HL, Jang JY, Lee H, Kim CG, Shin WG, Shin ES, Lee YC. Korean College of Helicobacter and Upper Gastrointestinal Research. Guidelines for the diagnosis and treatment of Helicobacter pylori infection in Korea, 2013 revised edition. J Gastroenterol Hepatol. 2014; 29:1371–1386.
Article
17. Fukase K, Kato M, Kikuchi S, Inoue K, Uemura N, Okamoto S, Terao S, Amagai K, Hayashi S, Asaka M. Japan Gast Study Group. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet. 2008; 372:392–397.
Article
18. Shin DW, Yun YH, Choi IJ, Koh E, Park SM. Cost-effectiveness of eradication of Helicobacter pylori in gastric cancer survivors after endoscopic resection of early gastric cancer. Helicobacter. 2009; 14:536–544.
Article
19. Tabuchi T, Ito Y, Ioka A, Miyashiro I, Tsukuma H. Incidence of metachronous second primary cancers in Osaka, Japan: update of analyses using population-based cancer registry data. Cancer Sci. 2012; 103:1111–1120.
Article
20. Curtis RE, Freedman DM, Ron E, Ries LA, Hacker DG, Edwards BK, Tucker MA, Fraumeni JF Jr. New malignancies among cancer survivors: SEER Cancer Registries, 1973-2000. Bethesda: National Cancer Institute;2006.
21. National Cancer Information Center. National cancer screening guideline for 7 major cancers [Internet]. Goyang: National Cancer Information Center;2015. cited 2016 February 4. Available from: http://www.cancer.go.kr/mbs/cancer/jsp/album/gallery.jsp?boardType=02&boardId=10243780&listType=02&mcategoryId=&id=cancer_010206000000&addCancerTitle=.
22. Lee JE, Shin DW, Lee H, Son KY, Kim WJ, Suh YS, Kong SH, Lee HJ, Cho B, Yang HK. One-year experience managing a cancer survivorship clinic using a shared-care model for gastric cancer survivors in Korea. J Korean Med Sci. 2016; in press.
Article
23. Shin DW, Kim YW, Oh JH, Kim SW, Chung KW, Lee WY, Lee JE, Lee WC, Guallar E, Cho J. Knowledge, attitudes, risk perception, and cancer screening behaviors among cancer survivors. Cancer. 2011; 117:3850–3859.
Article
24. Shin DW, Baik YJ, Kim YW, Oh JH, Chung KW, Kim SW, Lee WC, Yun YH, Cho J. Knowledge, attitudes, and practice on second primary cancer screening among cancer survivors: a qualitative study. Patient Educ Couns. 2011; 85:74–78.
Article
25. Kim YW, Yoon HM, Park JY. Gastric cancer survivorship. In : Seo HG, Park JH, editors. Evidence-based cancer survivorship management. Goyang: National Cancer Center;2013. p. 281–297.
26. Fujita Y, Tamada D, Kozawa J, Kobayashi Y, Sasaki S, Kitamura T, Yasuda T, Maeda N, Otsuki M, Okita K, Iwahashi H, Kaneto H, Funahashi T, Imagawa A, Shimomura I. Successful treatment of reactive hypoglycemia secondary to late dumping syndrome using miglitol. Intern Med. 2012; 51:2581–2585.
Article
27. Lee KU, Lee KY, Han SH. Effect of Camostat Mesilate in the treatment of reflux esophagitis after gastrectomy. Korean J Gastroenterol. 1998; 31:275–280.
28. Lim JS, Kim SB, Bang HY, Cheon GJ, Lee JI. High prevalence of osteoporosis in patients with gastric adenocarcinoma following gastrectomy. World J Gastroenterol. 2007; 13:6492–6497.
Article
29. Lim JS, Lee JI. Prevalence, pathophysiology, screening and management of osteoporosis in gastric cancer patients. J Gastric Cancer. 2011; 11:7–15.
Article
30. Lim JS, Jin SH, Kim SB, Lee JI. Effect of bisphosphonates on bone mineral density and fracture prevention in gastric cancer patients after gastrectomy. J Clin Gastroenterol. 2012; 46:669–674.
Article
31. Yang J, Li C, Liu H, Gu H, Chen P, Liu B. Effects of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on the clinical outcome of type 2 diabetes mellitus. J Surg Res. 2010; 164:e67–e71.
Article
32. Lee YH, Han SJ, Kim HC, Hyung WJ, Lim JS, Lee K, Lee HJ, Lee EY, Kang ES, Ahn CW, Cha BS, Lee HC. Gastrectomy for early gastric cancer is associated with decreased cardiovascular mortality in association with postsurgical metabolic changes. Ann Surg Oncol. 2013; 20:1250–1257.
Article
33. Earle CC, Neville BA. Under use of necessary care among cancer survivors. Cancer. 2004; 101:1712–1719.
Article
34. Shin DW, Park JH, Park JH, Park EC, Kim SY, Kim SG, Choi JY. Antihypertensive medication adherence in cancer survivors and its affecting factors: results of a Korean population-based study. Support Care Cancer. 2011; 19:211–220.
Article
35. Shin JY, Shim HY, Jun JK. Comparison of diabetes management status between cancer survivors and the general population: results from a Korean population-based survey. PLoS One. 2014; 9:e110412.
Article
36. Smyth EC, Capanu M, Janjigian YY, Kelsen DK, Coit D, Strong VE, Shah MA. Tobacco use is associated with increased recurrence and death from gastric cancer. Ann Surg Oncol. 2012; 19:2088–2094.
Article
37. Yang HK, Shin DW, Park JH, Kim SY, Eom CS, Kam S, Choi JH, Cho BL, Seo HG. The association between perceived social support and continued smoking in cancer survivors. Jpn J Clin Oncol. 2013; 43:45–54.
Article
38. Shin DW, Park JH, Kim SY, Park EW, Yang HK, Ahn E, Park SM, Lee YJ, Lim MC, Seo HG. Guilt, censure, and concealment of active smoking status among cancer patients and family members after diagnosis: a nationwide study. Psychooncology. 2014; 23:585–591.
Article
39. Bae JM. Nutritional consequences and management after gastrectomy. Hanyang Med Rev. 2011; 31:254–260.
Article
40. Sohn T. Nutritional treatment after gastrectomy. J Korean Med Assoc. 2010; 53:1124–1127.
Article
41. Scholmerich J. Postgastrectomy syndromes: diagnosis and treatment. Best Pract Res Clin Gastroenterol. 2004; 18:917–933.
42. Shin DW, Sunwoo S, Lee J. Management of cancer survivors in Korea. J Korean Med Assoc. 2015; 58:216–226.
Article
43. Rock CL, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya KS, Schwartz AL, Bandera EV, Hamilton KK, Grant B, McCullough M, Byers T, Gansler T. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin. 2012; 62:243–274.
Article
44. Shin DW, Kim Y, Park JH, Cho J, Jho HJ, Yang HK, Kim HS, Kim SY. Practices and predictors of 2009 H1N1 vaccination in cancer patients: a nationwide survey in Korea. Influenza Other Respir Viruses. 2012; 6:e120–e128.
Article
45. Han KH, Hwang IC, Kim S, Bae JM, Kim YW, Ryu KW, Lee JH, Noh JH, Sohn TS, Shin DW, Yun YH. Factors associated with depression in disease-free stomach cancer survivors. J Pain Symptom Manage. 2013; 46:511–522.
Article
46. Nordin K, Glimelius B. Psychological reactions in newly diagnosed gastrointestinal cancer patients. Acta Oncol. 1997; 36:803–810.
Article
47. Nordin K, Glimelius B, Pahlman L, Sjoden PO. Anxiety, depression and worry in gastrointestinal cancer patients attending medical follow-up control visits. Acta Oncol. 1996; 35:411–416.
Article
48. Shin DW, Kim SY, Cho J, Sanson-Fisher RW, Guallar E, Chai GY, Kim HS, Park BR, Park EC, Park JH. Discordance in perceived needs between patients and physicians in oncology practice: a nationwide survey in Korea. J Clin Oncol. 2011; 29:4424–4429.
Article
49. National Cancer Center. Recommendations for distress management in cancer patients. Goyang: National Cancer Center;2009.
50. Chang YW, Han YS, Lee DK, Kim HJ, Lim HS, Moon JS, Dong SH, Kim BH, Lee JI, Chang R. Role of Helicobacter pylori infection among offspring or siblings of gastric cancer patients. Int J Cancer. 2002; 101:469–474.
Article
51. Shin CM, Kim N, Yang HJ, Cho SI, Lee HS, Kim JS, Jung HC, Song IS. Stomach cancer risk in gastric cancer relatives: interaction between Helicobacter pylori infection and family history of gastric cancer for the risk of stomach cancer. J Clin Gastroenterol. 2010; 44:e34–e39.
52. Song M, Lee HW, Kang D. Epidemiology and screening of gastric cancer in Korea. J Korean Med Assoc. 2015; 58:183–190.
Article
Full Text Links
  • JKMA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr