Kidney Res Clin Pract.  2016 Mar;35(1):50-54. 10.1016/j.krcp.2015.11.001.

Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation

• Park WY
• Kang SS
• Park SB
• Park UJ
• Kim HT
• Cho WH
• Han S

• KMID: 2161502
• DOI: http://doi.org/10.1016/j.krcp.2015.11.001

Abstract

BACKGROUND
Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs.
METHODS
Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications.
RESULTS
During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups.
CONCLUSION
The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.

Keyword

Blood group incompatibility; Kidney transplantation; Spouses

MeSH Terms

Blood Group Incompatibility
Delayed Graft Function
Follow-Up Studies
Graft Rejection
Graft Survival
Humans
Incidence
Kidney Failure, Chronic
Kidney Transplantation*
Kidney*
Retrospective Studies
Spouses
Tissue Donors*
Transplants