Ann Dermatol.  2011 Oct;23(Suppl 2):S160-S164. 10.5021/ad.2011.23.S2.S160.

Cutaneous Extraskeletal Osteosarcoma on the Scar of a Previous Bone Graft

• Park SG
• Song JY
• Song IG
• Kim MS
• Shin BS

• KMID: 2156779
• DOI: http://doi.org/10.5021/ad.2011.23.S2.S160

Abstract

Extraskeletal osteosarcoma (ESOS) is a very rare malignant tumor of mesenchymal origin. It is rarer than osseous osteosarcoma and there are very few reports of the skin being a primary site. Most reported cutaneous ESOS were accompanied with metastasis in other organs. A 56-year-old man presented with a painful, 1.5x0.8 cm sized, brown-colored nodule on the right girdle area for 3 months. The histologic findings revealed a tumor that was confined to the dermis without connection to the subcutaneous tissue. In addition, there were large amounts of thin and lace-like bony trabeculae and osteoid with neoplastic cells in a highly pleomorphic sarcomatous stroma.

Keyword

Cutaneous; Extraskeletal; Osteosarcoma; Scar

MeSH Terms

Cicatrix
Dermis
Humans
Middle Aged
Neoplasm Metastasis
Osteosarcoma
Skin
Subcutaneous Tissue
Transplants

Figure

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  Fig. 1 Brown-colored cutaneous nodule on the linear scar of right girdle area.

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  Fig. 2 Extension of mid- to lower dermis by solid tumor (H&E, ×40).

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  Fig. 3 Microscopic finding of central portion of the tumor: a large amount of thin and lace-like bony trabeculae and osteoid with intervening malignant osteoblasts are seen (H&E, ×100).

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  Fig. 4 Microscopic finding of the periphery of the tumor: plump osteoid in a stroma of malignant tumor cells and osteoclast-like giant cells are observed (H&E, ×200).

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