Korean J Pathol.  2004 Oct;38(5):350-352.

Extraskeletal Osteosarcoma of the Posterior Mediastinum: A Case Report

• Han WC
• Cho HJ
• Lee JK
• Moon HB
• Ro JY

Abstract

Extraskeletal osteosarcoma is a rare malignant tumor of soft tissue. In addition, there are only several cases of osteosarcoma of the mediastinum as a primary site in the world. We report a case of extraskeletal osteosarcoma arising in the posterior mediastinum. A 54-year-old man visited our hospital because of chest pain. Chest CT showed a 12 cm sized huge mediastinal mass. The mass revealed solid and ivory-colored cut surface with multifocally ovoid cystic spaces and hemorrhage. Microscopically, the tumor consisted of polygonal stromal cells, giant cells and varying amounts of neoplastic new bone, and mitotic figures were frequently observed. There were no distant metastasis and regional lymph node involvement.

Keyword

Extraskeletal Osteosarcoma-Mediastinum

MeSH Terms

Chest Pain
Giant Cells
Hemorrhage
Humans
Lymph Nodes
Mediastinum*
Middle Aged
Neoplasm Metastasis
Osteosarcoma*
Stromal Cells
Tomography, X-Ray Computed