Ann Dermatol.  2008 Dec;20(4):250-253. 10.5021/ad.2008.20.4.250.

Localized Pseudoxanthoma Elasticum-like Changes on the Chin

• Lee JS
• Kim YC

• KMID: 2156407
• DOI: http://doi.org/10.5021/ad.2008.20.4.250

Abstract

Pseudoxanthoma elasticum (PXE) is a rare, inherited, multisystem disorder characterized by progressive calcification and fragmentation of elastic fibers. Typically, small, yellowish papules are located on the neck and flexural areas; however, localized acquired cutaneous PXE has been proposed as a non-heritable form of the disorder. We report a patient who had normal appearing skin on the chin with an itching sensation and had PXE-like changes by skin biopsy.

Keyword

Chin; Localized pseudoxanthoma elasticum

MeSH Terms

Chin
Elastic Tissue
Humans
Neck
Pruritus
Sensation
Skin

Figure

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  Fig. 1 A 60-year-old female with a 10-year history of pruritus on the chin.

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  Fig. 2 (A) Within the mid-dermis there are numerous small, fragmented, distorted elastic fibers (H&E stain, ×400). (B) Accumulation of swollen and irregularly clumped fibers staining deeply black with Verhoeff's stain (×400). (C) Staining for calcium with the von Kossa method was positive (×400).

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