Korean J Neurotrauma.  2013 Oct;9(2):120-124. 10.13004/kjnt.2013.9.2.120.

Risk Factors for Subsequent Fracture after Osteoporotic Vertebral Compression Fracture

• Kim SG
• Yang JC
• Kim TW
• Park KH

• KMID: 2156112
• DOI: http://doi.org/10.13004/kjnt.2013.9.2.120

Abstract

OBJECTIVE
Percutaneous vertebroplasty is an effective treatment that relieves pain caused by vertebral compression fracture. However, vertebroplasty may increase the risk for subsequent vertebral compression fracture. The purpose of this study is to evaluate the incidence of and risk factors for subsequent fracture after vertebroplasty.
METHODS
A retrospective analysis was performed for 112 patients who were diagnosed with a first osteoporotic compression fracture at a single level and underwent vertebroplasty at that level. Possible risk factors for subsequent fracture, such as age, sex, bone mineral density (BMD), location of treated vertebrae, pattern of cement distribution, cement volume, presence of intradiscal cement leakage, and direction of cement leakage, were analyzed.
RESULTS
During the follow-up period, 18 new subsequent vertebral fractures developed (16.1%). Subsequent fractures were more common in osteoporotic patients (T-score < or =-2.5)(p=0.034, r=0.208). Intravertebral cement volume > or =3.5 cc were also associated with a significantly higher risk of fracture (p=0.012, r=0.238).
CONCLUSION
Low BMD and volume of intravertebral cement were the factors most strongly associated with subsequent fracture after percutaneous vertebroplasty.

Keyword

Osteoporotic compression fracture; Bone mineral density; Cement volume

MeSH Terms

Bone Density
Follow-Up Studies
Fractures, Compression*
Humans
Incidence
Retrospective Studies
Risk Factors*
Spine
Vertebroplasty

Figure

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  FIGURE 1. Postoperative anteroposterior (A) and lateral (B) plain X-ray show evenly distributed cement in vertebral body.

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  FIGURE 2. Postoperative anteroposterior (A) and lateral (B) plain X-ray show partially augmented cement in vertebral body.

Reference

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