J Korean Orthop Assoc.  2016 Feb;51(1):91-95. 10.4055/jkoa.2016.51.1.91.

Diffuse-Type Giant Cell Tumor Arising from a Pretibial Lesion: Extra-Articular Pigmented Villonodular Tenosynovitis

• Kim JB
• Song IS
• Park BS
• Jeon TH

• KMID: 2154354
• DOI: http://doi.org/10.4055/jkoa.2016.51.1.91

Abstract

Pigmented villonodular synovitis (PVNS) is a rare, benign, soft tissue neoplasm affecting the synovium of joints, classified as localized and diffused type. Localized type is more common, arising from synovium of joints, bursae, and tendon sheaths. Diffused type is relatively rare, frequently arising from an extra-articular lesion, and sometimes from an intramuscular or subcutaneous lesion. Although the cause of occurrence is not yet clear, recently it has been known as a benign neoplasm rather than an inflammatory or reactive process. We performed a total excision of the PVNS in a pretibial lesion and achieved a good result. We report on the case with a review of the literature.

Keyword

tibia; pigmented villonodular synovitis; total synovectomy

MeSH Terms

Giant Cell Tumors*
Giant Cells*
Joints
Soft Tissue Neoplasms
Synovial Membrane
Synovitis, Pigmented Villonodular
Tendons
Tenosynovitis*
Tibia

Figure

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  Figure 1 Lateral radiograph shows a radiopaque lesion (circle) in the pretibial lesion, the left.

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  Figure 2 Magnetic resonance imaging findings. T: tibia, arrow: mass lesion. (A) Axial spin-echo T1-weighted image after contrast injection shows a focal hypointense area, findings that represent the blurring effect from hemosiderin. (B, C) Axial T1- and T2-weighted images show the localized intermediate signal intensity soft tissue mass at the same level.

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  Figure 3 Photograph of the resected specimen shows the brownish appearance caused by hemosiderin.

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  Figure 4 Microscopic finding. The picture shows multinucleated giant cells, hemosiderin deposits, and foam cells (H&E, ×400).

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