J Korean Ophthalmol Soc.  2015 Dec;56(12):1906-1912. 10.3341/jkos.2015.56.12.1906.

Comparison of Ocular Pulse Amplitude Measured Using Dynamic Contour Tonometry and Ocular Blood Flow Analyzer

• Kim YH
• Lee MV
• Ahn JH

• KMID: 2148753
• DOI: http://doi.org/10.3341/jkos.2015.56.12.1906

Abstract

PURPOSE
To compare ocular pulse amplitude (OPA) measured using dynamic contour tonometry (DCT) and ocular blood flow analyzer (BFA).
METHODS
Thirty-five eyes of 35 patients were enrolled in this cross-sectional and retrospective study. OPA was measured using DCT. Pulse amplitude (PA) and pulsatile ocular blood flow were measured using BFA.
RESULTS
OPA measured using DCT (2.79 +/- 0.89 mm Hg) was not significantly different from PA measured with BFA (3.02 +/- 0.90 mm Hg; p = 0.082) and both were significantly correlated (r = 0.663, p < 0.001). Mean difference +/- limit of agreement was -0.22 +/- 1.44 mm Hg between OPA and PA. OPA correlated significantly with intraocular pressure (IOP) measured using Goldmann applanation tonometry (r = 0.330, p = 0.047) but not PA (r = 0.057, p = 0.745). Both PA and OPA did not show significant correlation with the spherical equivalent of refractive error and central corneal thickness.
CONCLUSIONS
Although both OPA and PA measure IOP fluctuation and are not significantly different, they showed different relationships with IOP.

Keyword

Intraocular pressure; Ocular blood flow; Ocular pulse amplitude

MeSH Terms

Humans
Intraocular Pressure
Manometry*
Refractive Errors
Retrospective Studies

Figure

• 

  Figure 1. Agreement between intraocular pressure and ocular pulse amplitude measured by different devices. (A) Bland-Altman plot showing the inter-instrument repeatability of IOP measurements by DCT and GAT. (B) Bland-Altman plot showing the inter-instru-ment repeatability of IOP measurements by ocular BFA and GAT. (C) Bland-Altman plot showing the inter-instrument repeatability of IOP measurements by BFA and DCT. (D) Bland-Altman plot showing the inter-instrument repeatability of OPA measurements by DCT with measurements using BFA. GAT = Goldman applanation tonometry; IOP = intraocular pressure; DCT = dynamic contour tonometry; BFA = ocular blood flow analyzer; OPA = ocular pulse amplitude; PA = pulse amplitude measured by BFA; SD = standard deviation.

Reference

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