J Korean Ophthalmol Soc.  2015 Dec;56(12):1893-1898. 10.3341/jkos.2015.56.12.1893.

Choroidal Thickness at the Outside of Fovea in Diabetic Retinopathy Using Spectral-Domain Optical Coherence Tomography

• Lee SW
• Kim JS

• KMID: 2148751
• DOI: http://doi.org/10.3341/jkos.2015.56.12.1893

Abstract

PURPOSE
To evaluate choroidal thickness at the outside of the fovea in patients with diabetic retinopathy using spectral-domain optical coherence tomography.
METHODS
We examined 87 eyes of 87 patients with diabetic retinopathy and 40 eyes of 40 normal patients. Patients with diabetic retinopathy were divided into 3 groups according to the grade of diabetic retinopathy and macular edema. The choroidal thickness was obtained at the fovea and outside of the fovea using enhanced depth imaging of Spectralis optical coherence tomography. One foveal and 8 peripheral images were selected and choroidal thickness was measured from the outer border of the retinal pigment epithelium to the inner scleral border.
RESULTS
Subfoveal choroidal thickness was thinner with increasing severity of diabetic retinopathy. However, there was no significant difference between groups without the nasal side of the fovea. A statistically significant difference was observed over the fovea at the superotemporal area.
CONCLUSIONS
The choroidal thickness outside of the fovea was thinner with the severity of diabetic retinopathy and was more pronounced in the superotemporal area.

Keyword

Choroidal thickness; Diabetic retinopathy; Enhanced depth imaging; Optical coherence tomography

MeSH Terms

Choroid*
Diabetic Retinopathy*
Humans
Macular Edema
Retinal Pigment Epithelium
Tomography, Optical Coherence*

Figure

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  Figure 1. The study model about choroidal thickness of the fovea and posterior perivascular area. Choroidal thickness was measured at not only the fovea but also the superior, inferior, superonasal, inferonasal area from the fovea.

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  Figure 2. Graph of the average choroidal thickness under the fo-vea in normal subjects and patients with diabetic retinopathy (T1-4: 0.5/1.0/1.5/2.0 mm temporally apart from the fovea; N1-4: 0.5/1.0/1.5/2.0 mm nasally apart from the fovea). F = fo-vea; NPDR = nonproliferative diabetic retinopathy; DME = di-abetic macular edema; PDR = proliferative diabetic retinopathy.

Reference

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