J Korean Ophthalmol Soc.  2016 Aug;57(8):1216-1221. 10.3341/jkos.2016.57.8.1216.

Change in Subfoveal Choroidal Thickness after Patterned Panretinal Photocoagulation in Patients with Diabetic Retinopathy

• Jeon HM
• Chae SH
• Ahn SE
• Kim SW
• Yoon HS

• KMID: 2349066
• DOI: http://doi.org/10.3341/jkos.2016.57.8.1216

Abstract

PURPOSE
To evaluate changes in subfoveal choroidal thickness (SFCT) after patterned panretinal photocoagulation (PRP) using pattern scan laser (PASCAL) in patients with diabetic retinopathy.
METHODS
This study included 39 patients (50 eyes) treated with patterned PRP using PASCAL and who were followed for at least 3 months. Patients were classified into 2 groups according to severity: severe non-proliferative diabetic retinopathy and proliferative diabetic retinopathy. SFCT was measured by enhanced depth imaging of spectral-domain optical coherence tomography. The change in SFCT was analyzed at 1 and 3 months after PRP.
RESULTS
SFCT was 270.42 ± 61.44 µm before PRP, 264.52 ± 60.78 µm at 1 month, and 255.74 ± 56.89 µm at 3 months after PRP. Significant change of SFCT was found at 3 months after PRP. Central macular thickness was 275.56 ± 50.61 µm before PRP and increased to 295.18 ± 52.80 µm and 293.10 ± 57.24 µm at 1 and 3 months post-treatment, respectively. There were no significant differences between groups in SFCT at baseline or in the amount of change in SFCT after PRP.
CONCLUSIONS
SFCT significantly decreased after patterned PRP using PASCAL.

Keyword

Diabetic retinopathy; Panretinal photocoagulation; Pattern scan laser; Spectral-domain optical coherence tomography (SD-OCT); Subfoveal choroidal thickness

MeSH Terms

Choroid*
Diabetic Retinopathy*
Humans
Light Coagulation*
Tomography, Optical Coherence

Figure

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  Figure 1. Consecutive changes of the mean subfoveal choroidal thickness (SFCT) and central macular thickness (CMT) after patterned panretinal photocoagulation. Data are expressed as the mean ± standard error of mean. * p < 0.05 by repeated measures analysis of variance (ANOVA).

• 

  Figure 2. Scatter plots for correlation between subfoveal choroidal thickness (SFCT) and central macular thickness (CMT). (A) At 1 month after patterned panretinal photocoagulation (PRP), there was no significant correlation between SFCT and CMT (r = −0.133, p = 0.201). (B) At 3 months after patterned PRP, there was no significant correlation between SFCT and CMT (r = −0.184, p = 0.245). Compared by Pearson's correlation analysis. r = coefficient of correlation.

Reference

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